Chloroperoxidase Modified Electrode for Amperometric Determination of 2,4,6‐Trichlorophenol

Díaz-Díaz, Goretti; Blanco‐López, M. Carmen; Lobo-Castañón, Marı́a Jesús; Miranda‐Ordieres, Arturo J.; Tuñón‐Blanco, Paulino

doi:10.1002/elan.200804545

Cited by 27 publications

(13 citation statements)

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“…However, after electrochemical oxidation (over then þ 0.30 V), two reductive peaks around þ 0.20 and 0 V are observed at the third segment, respectively. In the previous reports, some quinone products have been reported after oxidation of phenol and phenol derivates [21,22]. Other reports have indicated a quinoneimine product produced after PAP oxidation [2,23].…”

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confidence: 93%

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

et al. 2010

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New determination scheme of p-aminophenol by using MnO 2 as a preoxidant is demonstrated in this work. In the flow injection system, the p-aminophenol is oxidized to quinoneimine by MnO 2 at up-stream, which can be detected at a suitable reductive potential. After optimization, the linear range of PAP is started from 1 mM to 30 mM (R 2 ¼ 0.999), the estimated detection limit (S/N ¼ 3) is 0.28 mM. Two real samples are studied and excellent recoveries are achieved by using standard addition method. The p-aminophenol (PAP) is a primary hydrolytic degradation product of acetaminophen (AC) [1], and AC is very widely used as analgesic and antipyretic drug to reduce fever, cough and cold. Moreover, p-aminophenol is very harmful for human body due to its structural similarity to aniline and phenol [2]. It is limited to a low level of 0.005% in the drug substance by the European Pharmacopoeia (Ph. Eur.) [3]. The PAP or PAP derivate compounds are common pollutants in effluents from cooking oil refineries, production of pesticides and herbicides, dyes and textiles, pharmaceuticals, pulp and paper, plastics, and detergent [4], because they are extremely toxic to aquatic life and impart a strong disagreeable taste to water [5]. Several researches have reported different PAP determination schemes including high performance chromatography (HPLC), capillary electrophoresis (CE) [6 -10], optical chemical sensors [11,12] and electrochemical sensor [13 -15]. Among the aforementioned schemes, the advantages of electrochemical scheme are low cost and less time consuming. Other applications of PAP are used as electroactive polymer film [16,17] in the determination of the ascorbic acid. But the poly-PAP film only shows the electroactive property in acid condition. In the neutral or alkaline condition, it is well known, the poly-PAP is accumulated onto electrode surface leading to the electrode inactivation and the hindrance of signal in further electroanalytical measurements. Thus, the determination of PAP in neutral or alkaline condition is very hard to avoid the formation of nonconductive film on the electrode surface. Some electrode surface cleaning schemes [18 -20] or chemical modified electrodes [13 -15] have been reported to solve this problem. However, the aforementioned electrode cleaning schemes are not convenient for further application and the pulse cleaning scheme may damage the electrode surface either.In this work, the MnO 2 was modified on a dummied upstream electrode as a preoxidant to selective oxidation of the PAP. Subsequently, the oxidized product is detected by the down-stream electrode. This simple scheme avoids the polymerization effect of the PAP with direct oxidative method. Two surface water samples collected from local pond and field were adopted as real samples. The flow injection analysis (FIA) coupled with MnO 2 modified electrode is used in PAP determination without enzyme modification, complicated sample treatment procedures and expensive electrode materials.The solid line of Figure 1A shows a ...

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confidence: 93%

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

et al. 2010

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“…Biosensors chemically modified with tyrosinase, laccase or peroxidase have the advantage of the specificity enzyme-substrate [23][24][25]. Biosensors based on aptamers and nucleic acids are also developed that are characterized by a high biomolecule-substrate specificity [26].…”

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Advantages of the Biomimetic Nanostructured Films as an Immobilization Method vs. the Carbon Paste Classical Method

et al. 2012

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Tyrosinase-based biosensors containing a phthalocyanine as electron mediator have been prepared by two different methods. In the first approach, the enzyme and the electron mediator have been immobilized in carbon paste electrodes. In the second method, they have been introduced in an arachidic acid Langmuir-Blodgett nanostructured film that provides a biomimetic environment. The sensing properties of non-nanostructured and nanostructured biosensors towards catechol, catechin and phenol have been analyzed and compared. The enzyme retains the biocatalytic properties in both matrixes. However, the nanostructured biomimetic films show higher values of maximum reaction rates and lowest apparent Michaelis-Menten constants. In both types of sensors, the sensitivity follows the decreasing order catechol > catechin > phenol. The detection limits observed are in the range of 1.8-5.4 μM for Langmuir-Blodgett biosensors and 8.19-8.57 μM for carbon paste biosensors. In summary, it has been demonstrated that the Langmuir-Blodgett films provide a biomimetic environment and nanostructured biosensors show better performances in terms of kinetic, detection limit and stability. OPEN ACCESSCatalysts 2012, 2 518

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“…TCP is the major metabolite of the insecticides chlorpyrifos and chlorpyrifos‐methyl, as well as trichlopyr herbicide . Since TCP is rapidly excreted in human urine after exposure to chlorpyrifos, it has been used as a biomarker for exposure , , , , . In Lin's group, a portable immunochromatographic strip‐based biosensor for direct detection TCP in human saliva sample was developed (Figure ) .…”

Section: Nanotechnology‐based Biosensors For Biological Monitoring Ofmentioning

confidence: 99%

Nanomaterial Based Biosensors for Detection of Biomarkers of Exposure to OP Pesticides and Nerve Agents: A Review

et al. 2017

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Organophosphorus (OP) pesticides are primarily used as insecticides and chemical warfare agents worldwide. Due to their impact on the environment and health, it is important to develop prompt and accurate pesticide analysis method. This review addresses recent advances and new trends in nanotechnology‐based biosensors for biological monitoring of exposures to OP pesticides and nerve agents. In order to determine them, we have to find the corresponding biomarkers. In 1989, the national academy of sciences (NAS)divided biomarkers into the following three categories: biomarker of exposure, biomarker of effect and biomarker of susceptibility (Figure 1A). The unique chemical and physical properties of nanomaterial have paved the way to new and improved sensing devices, in general, and electrochemical/optical biosensors, in particular. In this paper, background information and a general overview of electrochemical/immunoassay detection techniques are provided. Various nanomaterial labels are discussed. Usually nanomaterials can be roughly divided into nanometer powder, nanometer fiber, nanometer film, nanometer block and so on four classes, such as colloidal gold, semiconductor nanoparticles and carbon nanomaterial (Figure 1B). In addition, we discuss some future considerations and opportunities for advancing the use of biosensors for environmental and health studies.

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Chloroperoxidase Modified Electrode for Amperometric Determination of 2,4,6‐Trichlorophenol

Cited by 27 publications

References 18 publications

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

Advantages of the Biomimetic Nanostructured Films as an Immobilization Method vs. the Carbon Paste Classical Method

Nanomaterial Based Biosensors for Detection of Biomarkers of Exposure to OP Pesticides and Nerve Agents: A Review

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Chloroperoxidase Modified Electrode for Amperometric Determination of 2,4,6‐Trichlorophenol

Cited by 27 publications

References 18 publications

New Determination Scheme of p‐Aminophenol by MnO2 Modified Electrode Coupled with Flow Injection Analysis

New Determination Scheme of p‐Aminophenol by MnO2 Modified Electrode Coupled with Flow Injection Analysis

Advantages of the Biomimetic Nanostructured Films as an Immobilization Method vs. the Carbon Paste Classical Method

Nanomaterial Based Biosensors for Detection of Biomarkers of Exposure to OP Pesticides and Nerve Agents: A Review

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New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis

New Determination Scheme of p‐Aminophenol by MnO₂ Modified Electrode Coupled with Flow Injection Analysis