Cholesterol Trafficking and Distribution between Cellular Membranes

Determination of the size of lipid rafts studied through single-molecule FRET simulations

“…Cholesterol plays a key role in the stability, conformational order, and fluidity of the plasma membrane (6)(7)(8). Thus, the cholesterol level modulates the function of transmembrane proteins by modifying the membrane biophysical properties (9,10). Importantly, cholesterol could also modu-late the function of different proteins by direct interaction with them (11,12).…”