Chondroid syringoma: A case with unusual cytological findings

Abstract

Chondroid syringoma is a rare benign skin adnexal tumor, the cytological features of which have been published very rarely in the literature. A mucoid aspirate, abundant chondromyxoid matrix material, and epithelial components were suggested as diagnostic criteria. The reported case is one of chondroid syringoma confirmed by histopathology, the fine needle aspiration cytology of which yielded thin fluid-like material and microscopy revealed epithelial clusters with admixed smaller myoepithelial cells, background cyst macrophages, and only scanty chondromyxoid stromal elements. Including these cytological features of the present case among the diagnostic criteria for cytodiagnosis of chondroid syringomas might increase the chances of a definitive preoperative diagnosis and help in planning the extent of surgery.

Chondroid Syringoma of the Foot: A Rare Diagnosis

“…The former is much more common than the latter and shows a marked variation in the size and shape of the tubular lumina, in addition to cystic dilatation and branching. Embedded in an abundant stroma, the tubular lumina will be lined by 2 layers of epithelial cells: a luminal layer of cuboidal cells and a peripheral layer of flattened cells (8,22,23). Ultrasound and MRI findings were reported as nonspecific in formulating a direct diagnosis of a CS (24).…”

Fine-needle aspiration cytology of chondroid syringoma of fore arm: Report of a rare case

“…[ 1 3 ] Hirsch and Helwig introduced the name chondroid syringoma and subsequently used as alternate to the term mixed tumor of skin. [ 2 3 5 ] Chondroid syringomas are defined as benign adnexal tumors containing both epithelial and mesenchymal elements with histological resemblance to benign mixed tumors of salivary glands. [ 6 ]…”

“…Chondroid syringoma is a rare benign adnexal tumor of sweat gland origin. [ 1 2 ] It is also called benign mixed tumor of skin as it contains both epithelial and mesenchymal components. [ 1 2 ] Reported incidence of chondroid syringoma is 0.01-0.098% of all primary skin tumors.…”

“…[ 1 2 ] It is also called benign mixed tumor of skin as it contains both epithelial and mesenchymal components. [ 1 2 ] Reported incidence of chondroid syringoma is 0.01-0.098% of all primary skin tumors. [ 1 3 ] The most common presentation is a small, slow-growing, subcutaneous nodular mass in the head-neck region.…”

“…[ 1 3 4 ] Until now, only few cases of cytological diagnosis of chondroid syringoma have been reported. [ 1 2 ] Here, we are presenting a unique case of eccrine chondroid syringoma of forearm, diagnosed by fine-needle aspiration cytology (FNAC) and subsequently confirmed by histopathology.…”