Abstract:Chondroid syringoma is a rare, skin appendageal tumour, usually reported at the head and neck region. It is a mostly intradermal and rarely subcutaneous small painless nodule. The histopathological examination is characterized by a combination of epithelial and myoepithelial structures within a chondromyxoid and fibrous stroma. Herein, we present a rare case of chondroid syringoma with extensive bone formation.
“…The presence of bone formation and cartilage is seen in our case as depicted in Figure . Other skin lesions which show ossification include basal cell carcinomas, desmoplastic melanomas, cutaneous metastases, pilomatricomas, trichoepitheliomas, hemangiomas, nevi, epidermal cysts, schwannomas, lipomas, fibromas, epidermal, and dermoid cysts . In this case, although the lesion was very firm by palpation, FNA did not reveal any bone or cartilage fragments.…”
Section: Discussionmentioning
confidence: 63%
“…Bone formation is a rare finding in CS, and whenever present is usually focal and scant . Extensive ossification in CS is very rare, with only seven such tumors described in the literature, all located on the head . Associated marrow spaces comprised fibroadipose tissue without any hematopoiesis have been described .…”
Section: Discussionmentioning
confidence: 99%
“…Involvement of other parts of the body is very unusual . Extensive ossification in CS is a very rare feature, with only seven such cases documented, all occurring on the head . Herein, we report a case of CS of the axilla with extensive ossification.…”
Chondroid syringoma (CS) is a rare benign adnexal tumor of the skin with a resemblance to pleomorphic adenoma of salivary gland, most commonly involving the head and neck region. In the present literature, reports of the cytologic appearance of CS are scarce as it is rarely encountered by fine needle aspiration (FNA). A 67-year-old woman presented with a 1 year history of a 1 cm subcutaneous nodule in the right axilla. FNA biopsy was performed revealing an epithelial-mesenchymal biphasic neoplasm suggesting CS. Surgical excision confirmed the diagnosis and demonstrated extensive ossification, an extremely rare feature, with only seven reported cases, all located on the head. CS is a rare benign adnexal tumor of the skin, often overlooked due to its unremarkable clinical presentation. FNA is a reliable tool for the diagnosis of CS and helps guide optimal surgical management.
“…The presence of bone formation and cartilage is seen in our case as depicted in Figure . Other skin lesions which show ossification include basal cell carcinomas, desmoplastic melanomas, cutaneous metastases, pilomatricomas, trichoepitheliomas, hemangiomas, nevi, epidermal cysts, schwannomas, lipomas, fibromas, epidermal, and dermoid cysts . In this case, although the lesion was very firm by palpation, FNA did not reveal any bone or cartilage fragments.…”
Section: Discussionmentioning
confidence: 63%
“…Bone formation is a rare finding in CS, and whenever present is usually focal and scant . Extensive ossification in CS is very rare, with only seven such tumors described in the literature, all located on the head . Associated marrow spaces comprised fibroadipose tissue without any hematopoiesis have been described .…”
Section: Discussionmentioning
confidence: 99%
“…Involvement of other parts of the body is very unusual . Extensive ossification in CS is a very rare feature, with only seven such cases documented, all occurring on the head . Herein, we report a case of CS of the axilla with extensive ossification.…”
Chondroid syringoma (CS) is a rare benign adnexal tumor of the skin with a resemblance to pleomorphic adenoma of salivary gland, most commonly involving the head and neck region. In the present literature, reports of the cytologic appearance of CS are scarce as it is rarely encountered by fine needle aspiration (FNA). A 67-year-old woman presented with a 1 year history of a 1 cm subcutaneous nodule in the right axilla. FNA biopsy was performed revealing an epithelial-mesenchymal biphasic neoplasm suggesting CS. Surgical excision confirmed the diagnosis and demonstrated extensive ossification, an extremely rare feature, with only seven reported cases, all located on the head. CS is a rare benign adnexal tumor of the skin, often overlooked due to its unremarkable clinical presentation. FNA is a reliable tool for the diagnosis of CS and helps guide optimal surgical management.
“… 1 The presence of ossification in chondroid syringoma is exceedingly rare. 2 Dermatoscopy can provide an adjunctive measure for diagnosis of this adnexal neoplasm. The most predominant dermatoscopic feature for distinguishing dystrophic calcification and ossification in this tumor is the presence of white pleomorphic dots and globules, which, combined with the arborizing-like vessels, impart a marbled appearance.…”
Section: Histologic Diagnosismentioning
confidence: 99%
“… 1 Definitive treatment is by wide local excision with clear margins for prevention of recurrence. 2 Fig 3 Histopathology revealing multiple epithelial structures in a chondromyxoid stroma with irregular branching ducts and focal areas of calcification and ossification ( A - C , Hematoxylin-eosin stain; original magnifications: A, ×2; B , ×4; C, ×10). …”
BACKGROUND
Chondroid syringoma (CS) is a rare tumor of the apocrine or eccrine glands. CS of the lower back is rare, and its clinical manifestations are similar to those of lipoma, which is a common misdiagnosis for this disease.
CASE SUMMARY
A 39-year-old woman presented with a 2-year history of an asymptomatic subcutaneous mass on the lower back. The lesions increased progressively over time. The patient denied any history. Dermatological examination showed that there was a subcutaneous mass, ranging from 3-4 cm in diameter, with a clear boundary on the lower back. The surface of the skin was smooth without ulceration or scaling. Histopathologic examination was consistent with the diagnosis of CS.
CONCLUSION
CS is a rare tumor of the apocrine or eccrine glands. It usually presents as a wellcircumscribed and single subcutaneous masses. Histopathology showed the tumor was located in the dermis, with nests, sheets, and cords of basal-like cells, mucin deposition, and chondroid structures. We herein report a case of CS located in the lower back. CS of the lower back is rare, and its clinical manifestations are similar to those of lipoma, for which it is commonly misdiagnosed.
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