Chondrosarcoma of the Skull Base: A Case Study and Literature Review

Konovalov, A N; Shekhtman, O D; Ektova, Anastasia; Bezborodova, Tatyana

doi:10.7759/cureus.12412

Cited by 5 publications

(17 citation statements)

References 13 publications

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“…Surgery remains the primary treatment modality, ranging from curettage and bone grafting to wide excision or amputation, depending on the specific circumstances. Radiation therapy and chemotherapy are less commonly employed and are typically reserved for high‐grade or recurrent tumors 12 . A marginal resection is a surgical approach to remove a tumor with a minimal margin of healthy tissue, aiming to preserve functionality and minimize potential complications.…”

Section: Discussionmentioning

confidence: 99%

Distal radius chondrosarcoma in a 35‐year‐old female patient: A case report

Sahito,

Shah,

Zehra

et al. 2023

Clinical Case Reports

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Key Clinical MessageChondrosarcoma, although rare in the distal radius, poses significant challenges. Early diagnosis through incisional biopsy is essential. Surgical resection with margin control and fibular grafting can be effective, but vigilant surveillance is crucial due to its aggressive nature. Metastasis demands consideration of additional interventions or palliative care.AbstractChondrosarcomas constitute a rarity in the upper limbs, and their occurrence in the distal radius is even rarer with only one case previously documented. We report a case of distal radius chondrosarcoma in a 35‐year‐old female patient who presented with pain and swelling in her left wrist. Following an initial examination, an incisional biopsy was performed, confirming the diagnosis of dedifferentiated chondrosarcoma. The patient underwent a marginal resection of the distal radius and first carpal with ipsilateral fibular and locking compression plate fixation. Unfortunately, despite the interventions, the patient experienced recurrent swelling and ultimately required below‐elbow amputation, followed by above elbow amputation due to metastasis. Unfortunately, the patient passed away due to recurrence and metastasis.

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Section: Discussionmentioning

confidence: 99%

Distal radius chondrosarcoma in a 35‐year‐old female patient: A case report

Sahito,

Shah,

Zehra

et al. 2023

Clinical Case Reports

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“…Most of these arise in the skull base, developing from espheno-petrous and petro-clival synchondrosis that contain cartilage. Exceptionally, and based on isolated case reports, they can arise in convexity meninges; but the dura does not normally contain cartilage, so few hypotheses have been proposed about their origin like the presence of abnormal embryonal rests of cartilaginous tissue or multipotential mesenchymal cells in the meninges [ 2 , 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…Radical surgical resection is the treatment of choice, and adjuvant radiotherapy is often considered, especially after incomplete resection [ 8 , 9 ]. Therefore, the relevance of an appropriate pre-surgical diagnosis orientation could be very important when facing a dural mass as it may directly impact patient management.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the relevance of an appropriate pre-surgical diagnosis orientation could be very important when facing a dural mass as it may directly impact patient management. Indeed, some meningiomas can be managed with follow-up strategies, dural metastases can sometimes be treated with systemic oncologic treatments; while malignant mesenchymal tumors such as our case may directly go through a maximal safe resection and probably posterior adjuvant radiotherapy [ 8 , 9 , 11 , 12 ].…”

Section: Discussionmentioning

confidence: 99%

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Primary extraosseous dural chondrosarcoma: a case report

et al. 2021

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Background Dural chondrosarcoma is a very rare intracranial tumor, given that meninges do not normally contain cartilaginous tissue from which it can originate. We present a case of primary extraosseous dural chondrosarcoma. Case presentation A 48-year-old woman presented to our tertiary center neurosurgery consultation with progressive headache, vomiting, vertigo, and gait instability of 5 months’ duration. An initial brain CT revealed a large parietal mass with gross calcifications and subtle hyperostosis of the inner table. Subsequent brain MRI showed a heterogeneous expansive lesion with a honey-comb enhancement. Discussion of intra- or extra-axial location was warranted, and finally, initial presurgical suspicion of meningioma arose although some atypical imaging features were detected. The differential diagnosis included solitary fibrous tumor–hemangiopericytoma and dural metastasis. Total resection of the lesion was performed, extra-axial origin was confirmed, and pathology resulted in a primary dural chondrosarcoma. Conclusion The importance of this case presentation lies in the unusual nature of the final diagnosis, the brief literature review and differential diagnosis with emphasis on imaging pearls, as well as the useful reminder for physicians to consider less frequent diseases when key findings do not unambiguously lead to the usual suspects.

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“…При лечении остеосарком в дополнение к хирургическим методам лечения используют специализированные протоколы химиотерапии. При неполной резекции хондробластического варианта конвенциональной остеосаркомы в протокол лечения добавляют лучевую терапию [9,10].…”

Section: общая характеристика краниальных хондроидных опухолейunclassified

Morphological diagnosis of chondroid tumors of skull bones: аctual situation

Ektova

Рогожин

2021

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Cranial chondroid tumors are a large group of benign and malignant neoplasms. The histological diagnosis plays a crucial role for treatment of patients with this pathology, especially, for cases of tumors with uncertain malignancy such as atypical cartilaginous tumor / chondrosarcoma grade I. There is no description of a unified concept of morphological diagnosis of atypical cartilaginous tumor / chondrosarcoma grade I with cranial localization in the current medical literature today. In this article we tried to reflect the actual state of the problem and emphasize the relevance of standardization of criteria for the histological assessment of cranial chondroid tumors.

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Chondrosarcoma of the Skull Base: A Case Study and Literature Review

Cited by 5 publications

References 13 publications

Distal radius chondrosarcoma in a 35‐year‐old female patient: A case report

Distal radius chondrosarcoma in a 35‐year‐old female patient: A case report

Primary extraosseous dural chondrosarcoma: a case report

Morphological diagnosis of chondroid tumors of skull bones: аctual situation

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