Choroid plexus volume enlargement in first-episode antipsychotic-naïve schizophrenia
Jiaxin Zeng,
Tianwei Zhang,
Biqiu Tang
et al.
Abstract:Investigation of the choroid plexus in schizophrenia has seen growing interest due to its role in the interaction between neuroinflammation and brain dysfunction. Most previous studies included treated and long-term ill patients, while antipsychotics and illness course might both affect the choroid plexus. Here, we recruited first-episode antipsychotic-naïve schizophrenia patients, performed high-resolution structural brain scan and manually extracted choroid plexus volume. Choroid plexus volume was compared b… Show more
“…(2023) observed that a history of childhood trauma significantly moderates the relationship between inflammation and cognitive functioning in FEP ( 74 ). Furthermore, the increased size of the choroid plexus volume in antipsychotic-naïve FEP lends additional support to the significant influence of neuroinflammation on cerebral impairment ( 75 ).…”
Section: Low-level Inflammation and Neuroprogression In Schizophreniamentioning
“…(2023) observed that a history of childhood trauma significantly moderates the relationship between inflammation and cognitive functioning in FEP ( 74 ). Furthermore, the increased size of the choroid plexus volume in antipsychotic-naïve FEP lends additional support to the significant influence of neuroinflammation on cerebral impairment ( 75 ).…”
Section: Low-level Inflammation and Neuroprogression In Schizophreniamentioning
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