Choroidal Thickness in Healthy Children

Abstract

The data, obtained using enhanced depth imaging optical coherence tomography, provide the choroidal thickness profile of healthy children. The characteristic choroidal thickness profile in children suggests a redistribution process of choroidal tissue with aging.

Association of choroidal thickness with eye growth: a cross-sectional study of individuals between 4 and 23 years

“…11 Among these studies, only Park et al reported a negative correlation between SFCT and age. 9 However, Read et al 10 and Bidaut-Garnier et al 11 have reported that choroidal thickness increases significantly from early childhood to adolescence and is inversely correlated to AL in children. It is also important to emphasize that in Park et al 9 study, patients with SE þ / À 6 diopter were recruited, which was much higher SE refractive error compared with the inclusion criteria of other studies.…”

“…[15][16][17][18][19] Also, there is recent data on the hemodynamic effect of chemicals-sildenafil and nicotine-on choroid, obtained by OCT. 20,21 In our population of 160 patients aged 4-23 years, we found a mean SFCT of 308 mm with substantial variation between individuals, which was consistent with previous studies in adults. 4,22 Recent studies examining in vivo choroidal thickness with OCT in children have reported mean SFCT values of 348 mm (in 48 Korean children aged 4-10 years), 9 330 mm (in 194 children aged 4-12 years), 10 and 342 mm (in 174 children aged 3.5-15 years). 11 Among these studies, only Park et al reported a negative correlation between SFCT and age.…”

“…8 However, although our understanding of choroidal characteristics has increased substantially in recent years, only a few reports to date have provided values for choroidal thickness in children. [9][10][11] Recently, an increase in choroidal thickness with age but an inverse correlation of choroidal thickness with AL was also reported in healthy children aged 3.5-14.9 years. 11 Improved evaluation of normal choroidal thicknesses during eye growth should assist in the diagnosis of choroidal abnormalities associated with eye disease, and also allow us to understand the differences in the choroid during normal eye growth and the development of refractive error.…”

“…1 However, although our understanding of choroidal characteristics has increased substantially in recent years, only a few reports to date have provided values for choroidal thickness in children. [7][8][9] In a recent study, age and axial length (AL) were determined to be negatively correlated with choroidal thickness and volume in adults. 7 Similarly, in a previous study, we also demonstrated a decrease in choroidal thickness with increasing myopia, age, and AL in adults.…”

Choroidal Thickness and Volume in Healthy Young White Adults and the Relationships between them and Axial Length, Ammetropy and Sex

“…It is crucial to study repeatability and reproducibility because of the manual segmentation and the other mentioned parameters. Comparison with previous studies is difficult because of the different line scans performed with various instruments, variability in the ages and sexes of the populations being evaluated or the different statistical methodologies used.A number of studies have characterized healthy choroidal thickness, one of the most studied parameters, as having mean subfoveal choroidal thickness values lower than 300µm 7,9,10,20,23,25 or higher that 300µm 6,8,13,24,[26][27][28] , with a range from 202.6±83.5µm 9 to 355±73µm 8 or 354±111µm …”