Chronic angle closure glaucoma secondary to frail zonular fibres and spherophakia

Abstract

ABSTRACT.Purpose: We describe a 39-year-old Japanese woman with chronic angle closure glaucoma secondary to spherophakia and frail zonular fibres. The patient was 143 cm in height with short fingers and had no family history of eye problems. High intraocular pressure, total optic disc cupping and severe visual field constriction were found in the right eye. Case ReportA 39-year-old Japanese woman presented with decreased vision in her right eye on June 7, 2000. She had suffered high myopia bilaterally since childhood and her medical and familial histories were not significant. Her father and mother were 150 cm in height, while her two brothers were 155 cm and 160 cm in height. She was the eldest child and her parents were not relatives. She did not have any children and none of her family complained of eye trouble.The subject's visual acuity was 0.01 (0.

Cardiac findings in Weill–Marchesani syndrome

“…Two modes of inheritance have been reported: autosomal dominant (OMIM #608328) and autosomal recessive (OMIM #277600) [Faivre et al, 2003a]. The diagnosis is based on the clinical manifestations since there is no biochemical test or histological marker [Dietlein et al, 1998;Asaoka et al, 2003]. Recently, mutations in ADAMTS10 (in autosomal recessive cases) and in FBN1 (in autosomal dominant cases) have been reported in some WMS patients [Dagoneau et al, 2004].…”

A new combined surgical approach in a patient with microspherophakia and developmental iridocorneal angle anomaly

“…However, Yasar (2003) described a patient in whom lensectomy could control the IOP in the short-term, but who subsequently required trabeculectomy. Asaoka et al (2003) reported successful control of IOP with trabeculectomy in a patient with spherophakia and open angles . Kaushik et al (2006) reported that pupillary block can be relieved by lensectomy, but it may not suf¿ ce to control the IOP in the presence of extensive PAS.…”

“…IOP elevation in spherophakia can occur by a variety of mechanisms (Willoughby and Wishart, 2002;Kaushik et al, 2006;Asaoka et al, 2003). Angle-closure glaucoma occurs in spherophakia from a pupillary block mechanism caused by dislocation or forward movement of the lens, depending on the zonular integrity.…”

“…Different surgical management techniques comprises YAG-laser peripheral iridotomy (Bhattacharjee et al, 2010), lens extraction with phacoemulsi¿ cation with or without intraocular lens (IOL) and capsular tension ring implantation and anterior vitrectomy (Willoughby and Wishart, 2002;Bhattacharjee et al, 2010), pars plana lensectomy (PPL) and anterior vitrectomy (Kaushik S et al, 2006), goniosynechiolysis and lensectomy (Kanamori A, 2004) and trabeculectomy (Asaoka et al, 2003 andYasar, 2003) for glaucoma in microspherophakia.…”

Biometric and corneal topographic characteristics in patients with Weill-Marchesani syndrome

“…8 WeillMarchesani syndrome has been associated with other systemic problems such as thick skin, a muscular build, cardiac abnormalities, and mental retardation. 1,9 At present, the diagnosis of the syndrome is on the basis of clinical manifestations and there are no biochemical or histologic specifications that confirm the syndrome. 9,10 Despite clinical homogeneity, 2 modes of inheritance have been reported: autosomal dominant and autosomal recessive.…”