Chronic anterior uveitis in a patient with CREST syndrome

Cosío, Sara Fuente; Barca, Beatriz Arca; García, Paula Martínez; López, Antonio Sampedro

doi:10.1016/j.reumae.2018.10.021

Cited by 1 publication

(2 citation statements)

References 9 publications

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“…Only four cases of uveitis in CREST were reported in the literature 1 , 11 , 12 . The first case was described in 2000, a 73-year-old woman with unilateral granulomatous anterior uveitis in a set of CREST syndrome, treated successfully with topical steroids and mydriatics.…”

Section: Discussionmentioning

confidence: 99%

“…Systemic sclerosis (SSc) is a connective tissue disease characterized by cutaneous thickness and vasculopathy 1 . It is classified into two types: limited scleroderma to the skin and SSc with cutaneous and internal-organ manifestations and the less common SSc sine scleroderma with internal-organ manifestations but no skin involvement 2 .…”

Section: Introductionmentioning

confidence: 99%

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Recurrent uveitis in a patient with CREST syndrome: a case report

Khalayli,

Hodifa,

Tarcha

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction: Systemic sclerosis is a connective tissue condition, presented with clinical manifestations including ocular involvement in a small percentage. A few cases of uveitis were described in the literature, especially in CREST syndrome. Case presentation: We reported a case of a 48-year-old male with blurred vision of left eye that diagnosed with recurrent uveitis in the setting of CREST syndrome, treated with Prednisolone, Methotrexate, and Golimumab, with improvement. Discussion: Ocular manifestations of Systemic Sclerosis (SSc) include palpebral alterations, kerato-conjunctivitis, sicca syndrome, cataracts, pinguecula, and blepharitis. To our knowledge, this is the fifth case of uveitis in a setting of CREST syndrome in the literature, and the first one in sex involvement, as the previous cases were females, and in its treatment by Golimumab, an anti-TNF inhibitor. Conclusion: Although this association is low, we believe that it should be taken into consideration when treating these situations to obtain better treatment results. Collaboration between rheumatologists and ophthalmologists is necessary in deciding on treatment.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%