Chronic diseases and geriatric syndromes: The different weight of comorbidity

Vetrano, Davide Liborio; Foebel, Andrea D.; Marengoni, Alessandra; Brandi, Vincenzo; Collamati, Agnese; Heckman, George A.; Hirdes, John P.; Bernabei, Roberto; Onder, Graziano

doi:10.1016/j.ejim.2015.10.025

Cited by 77 publications

(81 citation statements)

References 30 publications

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“…11 In addition, comorbidity is not always associated with an increased number of geriatric syndromes. 12 We aimed to study the association of geriatric syndromes such as frailty, HoD and ACS that are measured in routine clinical care with hospital outcomes (prolonged LOS, inpatient mortality, delayed discharge, institutionalization, and 30-day readmission), while controlling for demographics (age, gender), AIS, comorbidity, and discharging specialty (general medicine, geriatric medicine, surgery).…”

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confidence: 99%

The Association of Geriatric Syndromes with Hospital Outcomes

Romero-Ortuño

Forsyth

Wilson

et al. 2017

Journal of Hospital Medicine

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confidence: 99%

The Association of Geriatric Syndromes with Hospital Outcomes

Romero-Ortuño

Forsyth

Wilson

et al. 2017

Journal of Hospital Medicine

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“…3,4 Bad habits acquired in youth such as sedentarism and poor diet increase susceptibility to chronic diseases in adulthood. [5][6][7] Among the chronic diseases that affect the aging process are Alzheimer's disease, depression, diabetes, systemic arterial hypertension, and heart disease. 8 In the people of this age group, several ill-de ned factors predispose them to unintentional falls that subsequently lead to impaired activities of daily living and an increase in mortality.…”

Section: Page 3/13mentioning

confidence: 99%

Effects of metabolic syndrome on the correlation between the most common groups of prescribed medications and the risk of fall in Brazilian elderly people

Souza

Silva²,

Vasconcelos³

2020

Preprint

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Background Aging is an irreversible process of all living beings and one of the great challenges we have to face is learning how to live healthier. Several health conditions, such as cardiovascular disease, diabetes, stroke, depression, hypertension, metabolic disorders, and falls, are related to senescence and can directly affect quality of life around the world. In addition to these physiological disorders, the use of medications can directly affect the quality of life of the elderly, and some studies have already reported the correlation between metabolic syndrome, prescription medications, and injury caused by falling. Methods This study was conducted with a group of 102 adults over 60 years of age, including volunteers in the city of Viçosa - Minas Gerais, Brazil. The instruments of analysis were performed using three types of tests: The Timed Up and Go (TUG) test, the Functional Reach Test, and the Tandem Test. Two questionnaires were used - the Falls Efficacy Scale-International (FES-I) and quality of life questionnaire (the Short Form [SF]-36) - in order to establish a connection between the intake of prescription of medication and the quality of life of this population. The statistical analysis was performed using R software version 3.2.2. Results The analysis of factors indicated that risk of fall was directly related to the amount of medications used by patients. The medicines associated with the risk of falls were grouped into nine categories: 28%, antihypertensive; 17%, anti-cholesterolemic; 8%, cardiovascular agents; 2%, musculoskeletal pain; 2%, hormones; 14%, central nervous system agents;6%, vitamins, 8%,anti-diabetic; and 15%, other target action medication. When the risk of fall was compared according to each category, the most significant difference in proportion was observed when related to central nervous system. Conclusion The data analysis showed that type of medications prescribed should be considered to better understand how some are related to the risk of fall in elderly people. The knowledge of how some prescribed medications can affect the way of life in the elderly community helps to guide some clinicians’ orientations to prevent possible injuries.

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“…В свою очередь, хроническая комор-бидность, особенно гипертензия, сахарный диабет (СД), деменция, хроническая обструктивная болезнь лег-ких, сердечная недостаточность, ишемическая болезнь сердца, фибрилляция предсердий, рак и дисфункция щитовидной железы способствуют развитию гериат-рических синдромов (головокружение и высокий риск падений, когнитивные дисфункции, депрессия, анемия, недержание мочи, нарушения сна и др.) [19].…”

Section: коморбидностьunclassified