Chronic Hepatitis After Hepatitis E Virus Infection in a Patient With Non-Hodgkin Lymphoma Taking Rituximab

Chronic Hepatitis E Virus Infection and Treatment

“…3,24,30,41,83,84 The clinical and laboratory features of chronic HEV in these patients are similar to those in recipients of a SOT. A few cases have been treated successfully with pegylated interferon or ribavirin as monotherapies.…”

“…4,[62][63][64][65][66][67][68][69][70][71][72] In contrast to recipients of a SOT, the key risk factor that determines the development of chronic infection in HIV patients is a low CD4 count. In the five chronic cases described so far, all had CD4 counts <250 mm 3 . As in transplant recipients, patients with chronic HEV had no symptoms attributable to HEV, the only clue to diagnosis was low-grade fluctuating transaminitis with alanine aminotransferase within the 100-300 IU/L range.…”

“…This review summarizes our current knowledge of chronic HEV infection, its treatment, and the extra-hepatic manifestations induced by HEV. ( J CLIN EXP HEPATOL 2013;3:134-140) I t is now realized that HEV infection not only causes a self-limiting infection, 1 but can also evolve to chronic hepatitis in immunosuppressed patients, i.e., patients with a solid-organ transplant (SOT), 2 hematological patients, 3 and HIV-positive patients. 4 In addition, HEVinduced extra-hepatic manifestations have been reported.…”

Chronic hepatitis E: A brief review

“…Ollier et al [43] reported a case of chronic hepatitis E in a 77 years old male with non-Hodgkin's lymphoma who was on rituximab. le Coutre et al [44] reported a case of reactivation and long term persistence of HEV viremia fourteen weeks after allogenic stem cell transplant (SCT) in a patient with Philadelphia chromosome positive acute lymphoblastic leukemia (ALL).…”

Hepatitis E virus infection in Iranian kidney-transplant patients

“…Genotype 1 is more prevalent in developing countries, whereas genotype 3 is more common in developed countries [1]. Chronic genotype 3 HEV infection can occur in solid-organ transplant patients [2], hematological patients who receive chemotherapy [3], and HIV-positive patients [4]. In the past several years, HEV infection in organ transplant patients has garnered much interest.…”