Chronic kidney disease and its health-related factors: a case-control study

Ghelichi-Ghojogh, Mousa; Fararouei, Mohammad; Seif, Mozhgan; Pakfetrat, Maryam

doi:10.1186/s12882-021-02655-w

Cited by 12 publications

(6 citation statements)

References 50 publications

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“…How thoroughly bone collagen is calcified during the formation stage of skeletal remodeling is reflected by mineralization. Inadequate vitamin D intake, mineral (calcium or Pi) insufficiency, acidosis, and aluminum toxicity are causes of poor mineralization (21).…”

Section: Underbjerg Et Al (mentioning

confidence: 99%

Assessment of Some Bone Turnover in Chronic Kidney Disease Patients in Tikrit/Iraq

2023

JPTCP

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The present study aimed to assess some bone turnover in chronic kidney disease with and without hemodialysis. 50 individuals were involved in the study and divided into three groups; the first two groups were patients with chronic kidney disease (15 were with hemodialysis, and 15 were without hemodialysis), and the third group involved 20 healthy individuals as a control group. Some bone turnovers like parathyroid hormone, vitamin D3, insulin-like growth factor-1, osteopontin, fibroblast growth factor-23, and calprotectin were analyzed using serum from all individuals. The serum concentration of parathyroid hormone was significantly lower (P>0.05) in chronic kidney disease with non-hemodialysis compared to chronic kidney disease with hemodialysis group and healthy individuals. While serum concentrations of vitamin D3, insulin-like growth factor, and osteopontin were significantly lower in both chronic kidney disease groups compared to healthy individuals. The serum concentration of fibroblast growth factor showed a non-significant difference (P<0.05) in both chronic kidney disease groups compared to healthy individuals. While serum concentration of calprotectin showed a significant increase (P>0.05) only in the chronic kidney disease without hemodialysis group compared to both other groups.

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Section: Underbjerg Et Al (mentioning

confidence: 99%

Assessment of Some Bone Turnover in Chronic Kidney Disease Patients in Tikrit/Iraq

2023

JPTCP

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“…6 Urmia Health center, Urmia University of Medical Sciences, Urmia, Iran. 7 Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.…”

Section: Supplementary Informationmentioning

confidence: 99%

“…The prevalence of ESRD (End Stage Renal Disease) is currently increasing as a global health problem in both developed and developing countries [1][2][3]. Chronic kidney disease (CKD) is a disease associated with irreversible kidney damage that can progress to ESRD (end-stage renal disease) [4][5][6][7][8]. ESRD is a destructive disorder that is associated with extreme mortality and cardiovascular complications, and certain problems such as developmental and psychosocial disorders occur in children, all of which severely affect quality of life [9,10].…”

Section: Introductionmentioning

confidence: 99%

The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis

et al. 2022

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Background This study is a systematic review and meta-analysis on published studies about the Global Survival Rate of Graft and Patients in the Kidney Transplantation of children. Methods Studies that investigated the survival rate of kidney transplants published until the 30th of December 2020 were selected using a systematic search strategy in the following databases: Medline, Embase, Scopus, ProQuest, ISI Web of Science, and Cochrane. The extracted data were entered into the Excel software and STATA 16.0. The search identified 6007 study references. From the total, we excluded 1348 duplicates, 3688 reference titles and abstracts that were deemed irrelevant, and 846 references that were not original articles (i.e., letter, commentary, review) or did not meet the inclusion criteria. As such, 89 studies involving 12,330 participants were included in this meta-analysis. Results In this study 1, 3, 5, 7 and 10-year survival rates of graft were estimated to be 92, 83, 74.40, 67.10, and 63.50%, respectively. Also, 1, 3, 5, 7 and 10-year survival rates of patients were estimated to be 99.60, 97.30, 95.20, 74.60, and 97.90%, respectively. Conclusions The findings suggest differences in graft and patient survival among children with kidney transplants. Although differences in ethnic origin, incompatibility with deceased donor kidneys, and types of kidney disease are unavoidable, interventions to improve preventive and living-donor transplantation are particularly needed in minority groups. In addition, more research is needed to establish and address the contribution of medical and sociocultural barriers to preferential treatment of these groups.

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“…End-stage kidney disease occurs when the functional capacity of the kidney is insufficient to filter out the toxins in the blood 7 . Multiple factors are responsible such as diabetes, hypertension, infection or acute vascular injury which reduces blood supply to the kidneys 8 , 9 . Over time this can lead to micro- and macrovascular organ damage as well as systemic vascular damage 10 .…”

Section: Introductionmentioning

confidence: 99%

Realtime monitoring of thrombus formation in vivo using a self-reporting vascular access graft

Hoare,

Kingsmore,

Holsgrove

et al. 2024

Commun Med

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Background Chronic kidney disease (CKD) affects 10% of the global population costing over a hundred billion dollars per annum and leading to increased risk of cardiovascular disease. Many patients with CKD require regular haemodialyses. Synthetic arteriovenous grafts (AVG) are increasingly used to provide rapid vascular connection for dialysis. Initially, they have excellent patency rates but are critically limited by neointimal hyperplasia at the venous anastomosis, which drives subsequent thrombosis, graft failure and death. Methods Here, we describe a system in which electrical impedance spectroscopy sensors are incorporated circumferentially into the wall of a synthetic arteriovenous graft. This is combined with an implantable radiotelemetry system for data transmission outside the patient. The system was tested using monolayers of endothelial and smooth muscle cells as well as swine blood and clots with explanted human carotid artery plaques. Sensor testing was then performed in vitro and the device was implanted in vivo in female swine. Results The device can wirelessly report the accumulation of biological material, both cells and blood. Differences are also detected when comparing controls with pathological atheroma. In swine differences between blockage formation in a graft were remotely obtained and wireless reported. Conclusions Combining electrical impedance spectroscopy and an implantable radiotelemetry system enables graft surveillance. This has the potential to be used for early detection of venous stenosis and blood clot formation in real-time in vivo. In principle, the concept could apply to other cardiovascular diseases and vascular implantable devices.

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Chronic kidney disease and its health-related factors: a case-control study

Cited by 12 publications

References 50 publications

Assessment of Some Bone Turnover in Chronic Kidney Disease Patients in Tikrit/Iraq

Assessment of Some Bone Turnover in Chronic Kidney Disease Patients in Tikrit/Iraq

The global survival rate of graft and patient in kidney transplantation of children: a systematic review and meta-analysis

Realtime monitoring of thrombus formation in vivo using a self-reporting vascular access graft

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