Chronic Nonleukemic Myelosis

Aleukaemic Myeloblastic Leukaemia

“…This type of case has been well discussed in recent years by Heller et al (1947), Merskey (1949), Dameshek (1951), Hutt et al (1953), and Black-Schaffer and Stoddard (1953). These authors have strested the close relationships which these cases have to chronic myeloid leukaemia on the one hand and polycythaemia on the other.…”

Treatment of Patients with Myelosclerosis

“…Some believe that most cases of osteosclerosis or myelosclerosis are atypical forms of chronic granulocytic leukaemia (Custer, 1949). Others have suggested that myelosclerosis and osteosclerosis may be due to alterations in the undifferentiated cells of the bone marrow, of unknown origin, comparable to the alterations which cause increase in leucoblasts and erythroblasts (Vaughan and Harrison, 1939;Merskey, 1949;Moeschlin, 1951Robson, 1952. The reduction in the degree of osteosclerosis of one of my patients under x-ray treatment supports this view, if it can be confirmed in other cases.…”