“…The chronic obstructive pulmonary disease (COPD) is one of the most common and widely-spread chronic diseases in the world (7.6 %) associated with a heavy economic burden [1]. According to the recent analysis of pathogenesis, the COPD is considered a multi-system disorder or systemically manifested disorder, since a long-standing chronic inflammation of the respiratory pathways, as well as chronic disorders of pulmonary ventilation, provokes a cascade of pathogenic modifications in the pulmonary tissue, other organs and systems including the cardiovascular, locomotor and other ones [2][3][4].…”