Chronic obstructive pulmonary disease, anxiety, and depression: State of the science

Putman-Casdorph, Heidi; McCrone, Susan

doi:10.1016/j.hrtlng.2008.02.005

Cited by 91 publications

(57 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Chronic lower pulmonary disease is a group of disorders characterized by a progressively declining lung function which has been associated with depression, anxiety and suicidal ideation [45,46,47]. To our knowledge, this is the first time that chronic lower pulmonary disease has been associated with a particular subtype of depression, namely the non-psychotic rather than the psychotic.…”

Section: Discussionmentioning

confidence: 99%

The Association between Physical Morbidity and Subtypes of Severe Depression

Østergaard

Petrides

Dinesen

et al. 2012

Psychother Psychosom

View full text Add to dashboard Cite

Background: Physical illness and depression are related, but the association between specific physical diseases and diagnostic subtypes of depression remains poorly understood. This study aimed to clarify the relationship between a number of physical diseases and the nonpsychotic and psychotic subtype of severe depression. Methods: This is a historical prospective cohort study. The study population consisted of all patients diagnosed with ICD-10 severe depression, either nonpsychotic or psychotic subtype, in Danish psychiatric hospitals between 1994 and 2008. The patients’ history of physical disease was assessed using the Danish National Patient Register. Using logistic regression it was investigated whether specific physical diseases were associated with relative increased risk for subsequent development of either the nonpsychotic or psychotic depressive subtype. Results: A total of 24,173 patients with severe depression were included in the study. Of those, 8,260 (34%) were of the psychotic subtype. A history of the following physical diseases, as opposed to their absence, increased the relative risk for subsequent development of the nonpsychotic compared to the psychotic depressive subtype [adjusted incidence odds ratio (AIOR) nonpsychotic vs. psychotic]: ischemic heart disease (AIOR = 1.3, p < 0.001), hypertension (AIOR = 1.2, p = 0.008), stroke (AIOR = 1.2, p = 0.042) and chronic lower pulmonary disease (AIOR = 1.2, p = 0.005). The total load of physical disease also increased the relative risk of nonpsychotic depression [AIOR = 1.05 (per disease), p = 0.001]. Conclusions: This study revealed that, in severe depression, a history of physical disease increased the relative risk of the nonpsychotic rather than the psychotic subtype.

show abstract

Section: Discussionmentioning

confidence: 99%

The Association between Physical Morbidity and Subtypes of Severe Depression

Østergaard

Petrides

Dinesen

et al. 2012

Psychother Psychosom

View full text Add to dashboard Cite

show abstract

“…However, evidence for the efficacy of antidepressant treatments would be stronger when specifically shown in patients with comorbid depression and COPD. Therefore, the aims of this review are to: 1) review and critically discuss whether the risk of major depression is increased in patients with COPD; 2) review the risk of suicidal behaviour in patients with COPD; 3) give a critical overview of the evidence for efficacy of pharmaco-and psychotherapy in depressed patients with COPD, based on available reviews and more recent studies [7][8][9][10][11]; and 4) provide practical recommendations concerning the diagnosis of and treatment for depression in patients with COPD.…”

Section: Introductionmentioning

confidence: 99%

Depression and suicidality in COPD: understandable reaction or independent disorders?

Hegerl

Mergl

2014

Eur Respir J

View full text Add to dashboard Cite

Both depression and chronic obstructive pulmonary disease (COPD) are prevalent, severe and often comorbid disorders. There is a risk of undertreatment for depression in patients with COPD as depressive symptoms, including suicidal tendencies, can erroneously be conceptualised as an understandable reaction to COPD and not as signs of an independent depressive disorder. In this context, the comorbidity rates of COPD and depression, the risk of suicidal behaviour in patients with COPD, and the evidence base for pharmaco-and psychotherapy in these patients are reviewed.Because symptoms of depression and COPD overlap it remains unclear how far the prevalence of major depression in COPD exceeds that in the general population. The suicide risk appears to be increased in COPD. Methodological studies providing evidence for the antidepressant efficacy of antidepressants or psychotherapy in patients with COPD are lacking. Recommendations for clinicians on how to separate depression from an understandable reaction to COPD are provided.Given the profound effects of depression on quality of life, life expectancy, COPD prognosis and suicide risk it is important to carefully diagnose and treat depression in patients with COPD according to national guidelines. @ERSpublications Comorbid depression has profound effects on COPD prognosis and should not be seen as understandable reaction to COPD

show abstract

“…In our study the HADS questionnaire [17] revealed unexpectedly high scores. About 90% of patients displayed a depressive mood at baseline according to threshold values from the literature [18,19,20].…”

Section: Discussionmentioning

confidence: 49%

Long-Term Efficacy of Pulmonary Rehabilitation in Patients with Occupational Respiratory Diseases

Ochmann¹,

Kotschy-Lang

Raab

et al. 2012

Respiration

View full text Add to dashboard Cite

Background: Pulmonary rehabilitation is a well-recognized treatment option in chronic obstructive lung disease improving exercise performance, respiratory symptoms and quality of life. In occupational respiratory diseases, which can be rather cost-intensive due to the compensation needs, very little information is available. Objectives: This study aims at the evaluation of the usefulness of pulmonary rehabilitation in patients with occupational respiratory diseases, partly involving complex alterations of lung function and of the sustainability of effects. Methods: We studied 263 patients with occupational respiratory diseases (asthma, silicosis, asbestosis, chronic obstructive pulmonary disease) using a 4-week inpatient rehabilitation program and follow-up examinations 3 and 12 months later. The outcomes evaluated were lung function, 6-min walking distance (6MWD), maximum exercise capacity (Wmax), skeletal muscle strength, respiratory symptoms, exacerbations and associated medical consultations, quality of life (SF-36, SGRQ), anxiety/depression (HADS) and Medical Research Council and Baseline and Transition Dyspnea Index scores. Results: Compared to baseline, there were significant (p < 0.05) improvements in 6MWD, Wmax and muscle strength immediately after rehabilitation, and these were maintained over 12 months (p < 0.05). Effects were less pronounced in asbestosis. Overall, a significant reduction in the rate of exacerbations by 35%, antibiotic therapy by 27% and use of health care services by 17% occurred within 12 months after rehabilitation. No changes were seen in the questionnaire outcomes. Conclusions: Pulmonary rehabilitation is effective even in the complex settings of occupational respiratory diseases, providing sustained improvement of functional capacity and reducing health care utilization.

show abstract

Chronic obstructive pulmonary disease, anxiety, and depression: State of the science

Cited by 91 publications

References 67 publications

The Association between Physical Morbidity and Subtypes of Severe Depression

The Association between Physical Morbidity and Subtypes of Severe Depression

Depression and suicidality in COPD: understandable reaction or independent disorders?

Long-Term Efficacy of Pulmonary Rehabilitation in Patients with Occupational Respiratory Diseases

Contact Info

Product

Resources

About