Abstract:Since 1999, clinical trials have more precisely defined the impact of various treatments on important patient-centred outcomes, allowing the development of treatment guidelines and leading to personalised treatment. The use of larger populations, seen in the Toward a Revolution in COPD Health (TORCH), Understanding Potential Long-Term Impacts on Function with Tiotropium (UPLIFT) and The Study to Understand Mortality and Morbidity (SUMMIT) trials, has allowed hypotheses to be answered clearly albeit not always … Show more
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