Chronic Periaortitis as a Systemic Autoimmune Disease

Suh, Chang‐Hee

doi:10.5772/19274

Cited by 1 publication

(1 citation statement)

References 80 publications

(116 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…dull abdominal pain, fever, fatigue, weight loss) and histologically similar (i.e. a thick fibro-inflammatory infiltrate rich in lymphocytes and collagen), some authors hypothesize a spectrum of the same disease [3]. Once considered a local complication of aortic atherosclerosis, chronic periaortitis seems rather to be a manifestation of a systemic disease (e.g.…”

Section: Introductionmentioning

confidence: 99%

Listeria monocytogenes infectious periaortitis: a case report from the infectious disease standpoint

et al. 2019

View full text Add to dashboard Cite

Background Endograft infection is a rare but extremely dangerous complication of aortic repair (25–100% of mortality). We describe here the first case of Listeria monocytogenes abdominal periaortitis associated with a vascular graft. We also discuss the differential diagnosis of periaortitis and provide a literature review of L. monocytogenes infectious aortitis. Case presentation Nine months after endovascular treatment of an abdominal aortic aneurysm (abdominal stent graft), a 76-year-old man was admitted for severe abdominal pain radiating to the back. Laboratory tests were normal apart from elevated C-reactive protein (CRP). Injected abdominal computed tomography (CT) showed infiltration of the fat tissues around the aortic endoprosthesis and aneurysmal sac expansion; positron emission tomography with 2-deoxy-2-[fluorine-18]fluoro- D-glucose integrated with computed tomography (18F-FDG PET/CT) showed a hypermetabolic mass in contact with the endoprosthesis. Blood cultures were negative. At surgical revision, an infra-renal peri-aortic abscess was evident; post-operative antibiotic therapy with ciprofloxacin and doxycycline was started. Cultures of intraoperative samples were positive for L. monocytogenes . Results were further confirmed by a broad-range polymerase chain reaction (PCR) and next-generation sequencing. Antibiotic treatment was switched to intravenous amoxicillin for 6 weeks. Evolution was uneventful with decrease of inflammatory parameters and regression of the abscess. Conclusion An etiologic bacterial diagnosis before starting antibiotic therapy is paramount; nevertheless, culture-independent methods may provide a microbiological diagnosis in those cases where antimicrobials are empirically used and when cultures remain negative.

show abstract

Section: Introductionmentioning

confidence: 99%