“…Mitochondria usually generate small quantities of superoxide by continuously converting 1 to 2% of consumed oxygen [9]. Mitochondria are generally protected from oxidative damage in several ways, including the activities of Mn-containing superoxide dismutase and glutathione peroxidase.…”
The present study demonstrates the renoprotective potential of 6-gingerol against cisplatin-induced oxidative stress and renal dysfunction in rats. Hence, 6-gingerol has a potential to be used as therapeutic adjuvant in cisplatin nephrotoxicity.
“…Mitochondria usually generate small quantities of superoxide by continuously converting 1 to 2% of consumed oxygen [9]. Mitochondria are generally protected from oxidative damage in several ways, including the activities of Mn-containing superoxide dismutase and glutathione peroxidase.…”
The present study demonstrates the renoprotective potential of 6-gingerol against cisplatin-induced oxidative stress and renal dysfunction in rats. Hence, 6-gingerol has a potential to be used as therapeutic adjuvant in cisplatin nephrotoxicity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.