1951
DOI: 10.1001/archinte.1951.03810120084008
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Chronic Scleroderma With Acute Exacerbation During Corticotropin Therapy

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Cited by 44 publications
(10 citation statements)
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“…The concern that corticosteroid use may exacerbate the clinical manifestations of SSc has been longstanding (10). A recent case-control study retrospectively reviewed the relationship of SRC to corticosteroid use in the 6 months preceding the onset of SRC (4).…”
Section: Discussionmentioning
confidence: 99%
“…The concern that corticosteroid use may exacerbate the clinical manifestations of SSc has been longstanding (10). A recent case-control study retrospectively reviewed the relationship of SRC to corticosteroid use in the 6 months preceding the onset of SRC (4).…”
Section: Discussionmentioning
confidence: 99%
“…Dating back to 1951, there has been concern about corticosteroids (CS) and their potential role in precipitating SRC in SSc [5]. Multiple case reports [6][7][8][9][10][11] and retrospective studies subsequently supported a possible association [12][13][14].…”
Section: Introductionmentioning
confidence: 99%
“…Of the several drugs commonly used to treat Scl, CSs have repeatedly been implicated in the development of SRC. 3,4 Their ability to inhibit prostacyclin production and to cause increased angiotensin-converting enzyme activity has been mechanisms implicated. 5 All the case reports of CS-induced SRC have been linked to the use of high-dose oral or parenteral CS, whereas topical and/or low-dose CS have never been implicated.…”
Section: Discussionmentioning
confidence: 99%