Ciba Foundation symposium on ionizing radiations and cell metabolism

Abstract

One important task for the biologist is to correlate the radiation effects obtained in experiments in vitro with those in living matter. Since enzymes are essential constituents of cells, this short survey of radiation effects on enzymes in vitro is meant to form a background against which the action of radiation in vivo should be viewed, and I hope that the following papers and their discussion will open new ways of approach to decide what part enzymes may play in the mode of action of radiation in living matter. As you will presently see, we shall have to consider not only radiation effects on enzymes themselves but also radiation effects on non-enzymic substances in their relation to enzymes.

Bioinformatics

“…Halocin production may be expected to be of considerable ecological advantage, as the ability to compete for nutrients and other resources may be enhanced by excreting archaeocins. [27][28][29][30][31] Comparative studies with large numbers of isolates have shown that there are several types of halocins with different activity spectra. 25 Protein antibiotics excreted by halophilic Archaea were first reported in 1982, when it was discovered that colonies of Haloferax mediterranei on agar plates inhibit growth of Halobacterium salinarum and other members of the Halobacteriaceae.…”

“…25 Protein antibiotics excreted by halophilic Archaea were first reported in 1982, when it was discovered that colonies of Haloferax mediterranei on agar plates inhibit growth of Halobacterium salinarum and other members of the Halobacteriaceae. GN 101,36 halocin A4 produced by a halophilic archaeon obtained from Tunisia, 29 and halocin S8 of a yet uncharacterized rod-shaped halobacterium isolated from Great Salt Lake. Since then it has become clear that halocin production is an almost universal feature among the halophilic Archaea.…”