Cigarette Smoking Behavior and Respiratory Alterations During Sleep in a Healthy Population

Casasola, G. García de; Álvarez-Sala, José Luis; Marques, José António; Sánchez-Alarcos, José; Tashkin, Donald P.; Espinós, D

doi:10.1007/s11325-002-0019-y

Cited by 28 publications

(22 citation statements)

References 21 publications

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“…The first publications were based on questionnaires without objective measures of smoking habits or sleep parameters (5-7,9,10), whereas more recent ones have focused on the participation of the severity category (pack-years) of current smokers affecting snoring and AHI (17)(18)(19)21). Only one study considered the effects on SaO 2 concentrations (19). Thus, the present study intended to clarify the repercussions of smoking severity, by current and former smokers, on objective sleep parameters.…”

Section: Discussionmentioning

confidence: 99%

“…Hoffstein (18) demonstrated that, although smoking status and amount of pack-years smoked was not associated with an increased AHI (18), there was a greater number of current smokers and average pack-years among individuals with AHI ≥50 than among those with AHI <10 (18). Finally, Casasola et al (19) reported that the nocturnal hypoxia Effect of smoking habits on sleep www.bjournal.com.br index was higher in current smokers than in non-smokers, and that the pack-years smoked index correlated significantly with carboxyhemoglobin concentration as well as the nocturnal hypoxia index (19). These studies notwithstanding, the literature (5-21) only partially responds to the question of whether and how smoking habits and sleep are related.…”

Section: Introductionmentioning

confidence: 97%

“…These studies notwithstanding, the literature (5-21) only partially responds to the question of whether and how smoking habits and sleep are related. Moreover, only a few studies considered the former smoking condition (17,18,20,21) or the number of packyears smoked (17)(18)(19). The purpose of the present study was to evaluate the effect of smoking status (current, former and non-smoker) and pack-years on objective sleep parameters, especially on respiratory parameters.…”

Section: Introductionmentioning

confidence: 98%

“…These disturbances are attributed to the stimulating effect of nicotine (7,8) and increased occurrence of snoring (9)(10)(11)(12)(13), even among passive smokers (14)(15)(16). The use of objective sleep parameters is restricted to only a few published studies (17)(18)(19)(20)(21).…”

Section: Introductionmentioning

confidence: 99%

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Effect of smoking habits on sleep

Conway

Roizenblatt

Palombini

et al. 2008

Braz J Med Biol Res

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To evaluate the effect of smoking habits on sleep, data from 1492 adults referred to the Sleep Institute were accessed and divided into 3 categories of smoking status: current, former and non-smokers. Categories of pack-years (<15 and ≥15) defined smoking severity. The association of smoking status and smoking severity with sleep was analyzed for sleep parameters, especially apnea and hypopnea index (AHI) ≥5, more than 5% of total sleep time (TST) spent with oxyhemoglobin saturation (SaO 2 ) <90%, and arousal index. The arousal index was higher among current (21 ± 17) and former smokers (20 ± 17) than non-smokers (17 ± 15; P < 0.04). Former smokers had a higher percent of TST at SaO 2 <90% than non-smokers (9 ± 18 vs 6 ± 13; P < 0.04). Former smokers with pack-years ≥15 compared to <15 exhibited higher AHI (22 ± 24 vs 16 ± 21; P < 0.05) and arousal index (22 ± 19 vs 18 ± 15; P < 0.05). Current smokers with pack-years ≥15 compared to <15 exhibited higher arousal index (23 ± 18 vs 18 ± 16; P < 0.05) and percent of TST at SaO 2 <90% (11 ± 17 vs 6 ± 13; P < 0.05). Smoking status and pack-years were not associated with AHI ≥5 on logistic regression analysis, but current smokers with pack-years ≥15 were 1.9 times more likely to spend more than 5% of TST at SaO 2 <90% than non-smokers (95%CI = 1.21-2.97; P = 0.005). The variability of arousal index was influenced by gender, AHI and current smokers with pack-years ≥15 (all P < 0.01). Smoking habits seem to be associated with arousal and oxyhemoglobin desaturation during sleep, but not with AHI. The effect was more pronounced in current than former smokers.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effect of smoking habits on sleep

Conway

Roizenblatt

Palombini

et al. 2008

Braz J Med Biol Res

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“…For example, carbon monoxide (CO) levels are significantly higher in smokers (Deveci et al, 2004) which is associated with lower effective hemoglobin concentrations and, consequently, diminished oxygen carrying capacity of the blood (Macdonald et al, 2004), as well as decreased efficiency of the mitochondrial respiratory chain (Alonso et al, 2004). Chronic smoking has also been equated to a type of repeated acute (mild) CO poisoning (Alonso et al, 2004), and is linked to nocturnal hypoxia (Casasola et al, 2002) as well as to respiratory risks such as chronic obstructive pulmonary disease and other conditions that may diminish or compromise lung function (Bartal, 2001). Decreased lung function was associated with poorer neurocognition and increased subcortical atrophy in community-dwelling adults aged 60−64 years (Sachdev et al, 2006).…”

Section: Potential Mechanisms For Neocortical Gm Dysmorphology In Conmentioning

confidence: 99%

Non-treatment-seeking heavy drinkers: Effects of chronic cigarette smoking on brain structure

Durazzo

Cardenas

Studholme

et al. 2007

Drug and Alcohol Dependence

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We previously reported [Cardenas, V.A., Studholme, C., Meyerhoff, D.J., Song, E., Weiner, M.W., 2005. Chronic active heavy drinking and family history of problem drinking modulate regional brain tissue volumes. Psychiatry Res. 138, 115−130] that non-treatment-seeking, active heavy drinkers (HD) demonstrated smaller regional neocortical gray matter volumes compared to light drinking controls; however, the potential effects of chronic cigarette smoking on regional brain volumes were not addressed. The goal of this retrospective analysis was to determine if chronic smoking affected brain structure in the non-treatment-seeking heavy drinking sample from our earlier report (i.e., Cardenas et al., 2005). Regional volumetric comparisons were made among age-matched smoking HD (n = 17), non-smoking HD (n = 16), and non-smoking light drinkers (nsLD; n = 20) from our original sample. Quantitative volumetric measures of neocortical gray matter (GM), white matter (WM), subcortical structures, and cerebral spinal fluid (CSF) were derived from high-resolution magnetic resonance imaging. Smoking HD demonstrated smaller volumes than nsLD in the frontal, parietal, temporal GM, and for total neocortical GM. Smoking HD also demonstrated smaller temporal and total GM volumes than non-smoking HD. Non-smoking HD and nsLD did not differ significantly on GM volumes. Further, the three groups did not differ on lobar WM, subcortical structures or regional CSF volumes. These retrospective analyses indicate neocortical GM volume reductions in non-treatment-seeking smoking HD, but not in non-smoking HD, which are consistent with our studies in recently detoxified treatment-seeking alcohol-dependent samples.

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The impact of active and former smoking on the severity of obstructive sleep apnea

et al. 2015

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Cigarette Smoking Behavior and Respiratory Alterations During Sleep in a Healthy Population

Abstract: Cigarette smoking does not seem to be associated with increased apneic activity during sleep. However, it is associated with a decrease in nocturnal oxygen saturation.

Cited by 28 publications

References 21 publications

Effect of smoking habits on sleep

Effect of smoking habits on sleep

Non-treatment-seeking heavy drinkers: Effects of chronic cigarette smoking on brain structure

The impact of active and former smoking on the severity of obstructive sleep apnea

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