Ciliary neurotrophic factor as a potential biomarker of cerebral pathologies
A. A. Gudkova
Abstract:Ciliary neurotrophic factor (CNTF) is a pluripotent neurotrophic factor with high neuroprotective potential, a neurocytokine that has demonstrated potential in the therapy of neurodegenerative, psychiatric and metabolic diseases. Preclinical data support the general concept of its potential neuroprotective and trophic effects, and recent clinical data support the potential role of CNTF in the treatment of neurodegeneration and obesity. A number of data indicate the involvement of CNTF in stress reactivity and … Show more
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