Circadian functioning and quality of life in substance use disorder patients with and without comorbid schizophrenia

Hashemzadeh, Iman; Navarro, José Francisco; Adán, Ana

doi:10.1016/j.pnpbp.2022.110623

Cited by 4 publications

(1 citation statement)

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“…The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality in patients with PD in a recent month. It consists of 19 items and generates 7 dimensions as follows: subjective sleep quality, sleep duration, medication use, sleep latency, efficiency of sleep, sleep disturbances, daytime dysfunction, and each dimension takes score from zero to three (Hashemzadeh et al, 2022). PSQI was reliable in distinguishing good and bad sleep habits, and showed strong reliability and validity in a variety of samples (Mollayeva et al, 2016).…”

Section: Patient Assessmentmentioning

confidence: 99%

How sleep quality affects activities of daily living in Parkinson’s disease: the mediating role of disease severity and the moderating role of cognition

Luo,

Liu,

Chen

et al. 2023

Front. Aging Neurosci.

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ObjectiveThe aim of this study was to explore the influential mechanism of the relationship between sleep quality and activities of daily living (ADL) in patients with Parkinson’s disease (PD), we hypothesized disease severity as a mediator and assumed the mediating process was regulated by cognition.Methods194 individuals with PD (95 women and 99 men) were enrolled in study. The Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality of PD patients. Patients’ ADL, disease severity and cognition were measured by the Unified Parkinson’s Disease Rating Scale-II (UPDRSII), Hoehn-Yahr (H-Y) Scale, and Mini-Mental State Examination (MMSE). We investigated the mediating role of disease severity and the moderating effect of cognition on the association between sleep quality and ADL in PD patients.ResultsThe score of UPDRSII was positively correlated with the score of PSQI and H-Y stage, while the score of MMSE was negatively correlated with the score of H-Y stage and UPDRSII. Sleep quality predicts disease severity, and disease severity predicts ADL. Disease severity mediated the relationship between sleep quality and ADL, and the mediating effect was 0.179. Cognition alone did not affect ADL, but the interaction between disease severity and cognition was significantly affected ADL, confirming the moderating effect of cognition in PD patients.ConclusionDisease severity mediated the association between sleep quality and ADL, good cognition significantly reduced disease severity’s mediating influence on the relationship between sleep quality and ADL. Our study indicated a close relationship between ADL and sleep and cognition in PD, and also provided new insights into the overall management of PD and a better quality of life of PD patients.

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Section: Patient Assessmentmentioning

confidence: 99%