Abstract:Introduction: Paediatric Cirrhosis-Sepsis (PC-S) patients attain early mortality. Plasma bacterial composition, the cognate metabolites and their contribution in the deterioration of PC-S patients to early mortality in unknown. We aimed to delineate the plasma metaproteome-metabolome landscape and identify molecular indicators capable of segregating PC-S patients predisposed to early mortality using untargeted metaproteomics-metabolomics by UHPLC-HRMS followed by validation using Machine learning (ML) algorith… Show more
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