2018
DOI: 10.1016/j.ijcard.2017.10.044
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Circulating microparticles are associated with clinical severity of persistent ST-segment elevation myocardial infarction complicated with cardiogenic shock

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Cited by 29 publications
(27 citation statements)
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“…This can lead to cardiac metabolic disorders, negative inotropic effects, ventricular dysfunction, and myocardial remodeling. Thus, neutrophils are positively associated with inflammation and have been used to evaluate the diagnosis and prognosis of diseases [ 30 , 31 , 32 ]. In contrast, lymphocytes exhibit a regulatory response of the immune system.…”
Section: Discussionmentioning
confidence: 99%
“…This can lead to cardiac metabolic disorders, negative inotropic effects, ventricular dysfunction, and myocardial remodeling. Thus, neutrophils are positively associated with inflammation and have been used to evaluate the diagnosis and prognosis of diseases [ 30 , 31 , 32 ]. In contrast, lymphocytes exhibit a regulatory response of the immune system.…”
Section: Discussionmentioning
confidence: 99%
“…Despite numerous publications, the exact pathways of different EVs remain largely unknown, and its study was outside of the framework of the present work. Future studies may explain functional relations between the increased release of EVs in patients with chronic or acute forms of CVD [20][21][22][23][24]71 , inflammatory activation 72,73 , and the worsening of the outcomes in patients with STEMI 25,26 .…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, we and others have found that the numbers of EVs of diverse origin are significantly increased in patients with different forms of CVD, especially in ACS [20][21][22][23][24] , and this increase is associated with the risk of development of CVD complications 25,26 . Changes in EV-associated cytokines have been reported for several pathologies including infectious diseases 17,18,27 .…”
mentioning
confidence: 84%
“…On the one hand, neutrophil, which is a vital type of leucocytes, has been well studied regarding the development of various diseases, including CS. Sionis et al 32 recently found that distinct microparticles released by neutrophils (CD15+) significantly increased in patients with CS. This result suggested high activation of neutrophils in CS and further indicated the significance of inflammation in that condition.…”
Section: Discussionmentioning
confidence: 96%