2024
DOI: 10.21037/tbcr-23-55
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Circulating tumor cells et al.: towards a comprehensive liquid biopsy approach in breast cancer

Eleonora Nicolò,
Caterina Gianni,
Letizia Pontolillo
et al.

Abstract: Liquid biopsy has emerged as a crucial tool in managing breast cancer (BC) patients, offering a minimally invasive approach to detect circulating tumor biomarkers. Until recently, the majority of the studies in BC focused on evaluating a single liquid biopsy analyte, primarily circulating tumor DNA and circulating tumor cells (CTCs). Despite the proven prognostic and predictive value of CTCs, their low abundance when detected using enrichment methods, especially in the early stages, poses a significant challen… Show more

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