2022
DOI: 10.51753/flsrt.1035228
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Citric acid production using rotating biodisc reactor (RBR)

Abstract: Citric acid is one of the most remarkable industrial goods fabricated by industrial fermentation using filamentous fungus. When Aspergillus niger, a filamentous fungus, is produced under suitable conditions, high amounts of citric acid are obtained. This study aims to explain the citric acid synthesis studied in a biodisc reactor using A. niger. Various physiological parameters have been investigated in order to determine the optimum citric acid synthesis in biodisc reactor. Optimum incubation time was found t… Show more

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Cited by 3 publications
(1 citation statement)
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“…The bioreactor system offers some key advantages such as allowing cultures to grow rapidly, promoting the bulk transfer of nutrients and gases, promising to scale up the process and save labor costs. Moreover, constant micro-environmental conditions and a high degree of automation of the cultivation process for a liquid medium can be provided by using the bioreactor systems ( Yancheva et al., 2019 ; Sidal, 2022 ). Similar to microbial and mammalian cell cultures grown in bioreactors that have fulfilled the requirements set by the FDA and EMEA over the past 20 years, plant cell cultures grown in bioreactors show advantages for the production of therapeutics ( Huang and McDonald, 2012 ).…”
Section: Tissue Culture-based Biotechnological Approaches For Obtaini...mentioning
confidence: 99%
“…The bioreactor system offers some key advantages such as allowing cultures to grow rapidly, promoting the bulk transfer of nutrients and gases, promising to scale up the process and save labor costs. Moreover, constant micro-environmental conditions and a high degree of automation of the cultivation process for a liquid medium can be provided by using the bioreactor systems ( Yancheva et al., 2019 ; Sidal, 2022 ). Similar to microbial and mammalian cell cultures grown in bioreactors that have fulfilled the requirements set by the FDA and EMEA over the past 20 years, plant cell cultures grown in bioreactors show advantages for the production of therapeutics ( Huang and McDonald, 2012 ).…”
Section: Tissue Culture-based Biotechnological Approaches For Obtaini...mentioning
confidence: 99%