“…For extensive disease, a combination of surgery, chemotherapy and radiation is advocated. Some recent therapeutic agents such as imatinib and matrix metalloproteinase inhibitors are also being tried 27 , 28 , 29 and some antiviral agents including ganciclovir, foscarnet, valganciclovir and cidofovir have been shown to have some therapeutic effects via inhibiting HHV‐8. 30 , 31 However, the best therapeutic approach for KS lesions in setting of PV is still remains to be elucidated.…”