Clathrin: Bender or bystander?

Abstract

Cell biologists have long debated the role of clathrin in curving membranes during endocytosis. New findings from Cail et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202109013) take an innovative approach to directly demonstrate the indispensable functions of both clathrin and its adaptor network in shaping endocytic vesicles.