Click gold quantum dots biosynthesis with conjugation of quercetin for adenocarcinoma exertion

Abstract

A cost-effective and eco-friendly click biosynthesis of small molecule quercetin–gold quantum dots (QRT–AuQDs) was developed involving quick conjugation, using an ultrasonication method at ambient temperature by utilizing QRT and gold ions in the molar ratio 0.1 : 1.

Recent updates in click and computational chemistry for drug discovery and development

“…Moreover, 5-fluorouracil-coumarin conjugation ( Figure 1E ) as anti-cancer drug candidate ( ópez et al, 2022 ) and pH responsive doxorubicin delivery polymers nano-particles ( Wallat et al, 2018 )for treatment of breast and ovarian cancer were generated by modification of natural products via CuAAC. In addition, quercetin-gold quantum dots for adenocarcinoma treatment ( Pansare et al, 2022 ) and chondroitin sulfate-multiarmed PEG hydrogels for skin tissue engineering ( Sousa et al, 2022 ) had been developed by modification of natural products ( Figure 1F ).…”

Economical gold recovery cycle from bio-sensing AuNPs: an application for nanowaste and COVID-19 testing kits

“…47 Metal-based herbal drugs show strong potency for treating different types of cancer cells. 48,49 However, some of the synthetic drugs exert severe side effects and possess inherent limitations possibly due to their toxicity, drug resistance, and covalent mode interaction with DNA molecules. [50][51][52] Major attention is therefore focused on designing new metal-based anticancer drugs showing the interaction with DNA 53 and these outcomes may find their application in the development of new antitumor drugs.…”