Clickable 2,2‐bis(hydroxymethyl)propionic acid‐derived AB₂ monomers: Hyperbranched polyesters through the CuAAC cycloaddition (click) reaction

Abstract

We present the synthesis and characterization of two aliphatic AB 2 monomers derived from the readily available 2,2-bis(hydroxymethyl)propionic acid and containing one alkyne group and two azide functionalities. The distance between the polymerizable groups differs in the two monomers by the insertion of an additional carbon atom in the aliphatic structure that addresses the steric demand during polymerization. The synthetic procedure for the monomers is relatively simple and scalable, and the monomers are able to polymerize through the Copper(I)-catalyzed Azide-Alkyne Cycloaddition (CuAAC reaction). The polymerization affords hyperbranched polymers in good yields and molecular weights and moderate degrees of branching.

Polylactic-Containing Hyperbranched Polymers through the CuAAC Polymerization of Aromatic AB2 Monomers

“…More recently, Gao and co-workers reported the CuAAC living chain-growth polymerization of AB 2 monomers for producing HPs with a controlled structure and low Ð [45][46][47]. Our group have used a CuAAC polymerization of AB 2 monomers from 2,2-bis(hydroxymethyl)propionic acid, in which the distance between the polymerizable groups was systematically changed and the effect on the DBs was studied [48].…”