With the development of urbanization, more and more commercial buildings are built in cities, which is resulting in a large amount of building energy consumption that threatens the ecological environment of the earth. Lighting energy in commercial buildings occupies a large proportion of consumption, and improving the quality of natural daylight in commercial atriums is of great significance for building energy efficiency as well as improving indoor comfort. This paper proposes a method for optimizing the daylight quality of commercial atriums. Starting from the perspective of parametric design, this paper investigates the current status and theoretical research on the natural daylight of commercial atriums in cold regions, taking Jinan, China, as an example. Dynamic daylight and glare simulations were performed using Rhino + Grasshopper and Ladybug + Honeybee for every design parameter in the system, followed by correlation analysis and multiple linear regression analysis using SPSS to determine the degree of influence of each design parameter on the daylight quality of the atrium. Based on the results of the above analysis, the multi-objective optimization plug-in Octopus is used to find the combination of design parameters that can achieve the best indoor daylight. The results show that among a total of fourteen atrium design parameters, seven of them are significantly correlated with atrium daylight, and after regression analysis, it is found that the atrium design parameters affect the atrium daylight and glare in the following order: Skylight VT, Skylight ratio, Atrium inclination, Fabric coverage, Fabric VT, Wall reflectivity, Roof reflectivity. The optimal design parameters for commercial atrium daylight quality are obtained according to the Pareto front solution set, which provides some reference and ideas for improving the optimization of commercial atrium daylight in cold regions of China.