clinic-radiological comparative study to evaluate of hard & soft tissue changes around dental implants placed with platelet rich fibrin in type-2 diabetic patients with varying glycemic levels

Abstract

Periodontitis is considered the "sixth complication" of diabetes and tooth loss is its inevitable result. Various studies have shown the prevalence of tooth loss to be more in diabetic patients. Poor glycemic levels have shown to affect the osseointegration of dental implants in diabetics, thus this study aimed to evaluate the regenerative and anti-inflammatory effects of Platelet rich Fibrin (PRF) on the peri-implant soft and hard tissue around dental implants in type 2 DM patients with varying glycemic levels. The study was conducted on patients who presented with a complain of missing tooth and required replacement of dentition with endosseous implants at department of periodontis at Rajasthan Dental College & Hospital, Jaipur, Rajasthan. A total of 20 implant sites were selected in 8 patients with age range of 20-65 years. Statistical analysis was carried out using Student t-test’ to compare soft tissue evaluation scores and crestal bone loss in both the group. Analysis of variance (ANOVA) was carried out to evaluate the significance between the test and control groups at baseline, 6 and 9 months.