2016
DOI: 10.1136/sextrans-2015-052453
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Clinical and epidemiological characterisation of lymphogranuloma venereum in southwest Spain, 2013–2015

Abstract: This analysis shows that LGV infections are occurring in MSM in southwest Spain, where no data about LGV have been described before, reinforcing the need for screening and genotyping for LGV. LGV should be taken into account when considering treatment and management of rectal C. trachomatis infections, including in asymptomatic HIV-positive MSM. Larger studies on appropriate treatment for asymptomatic LGV infection are needed.

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Cited by 21 publications
(11 citation statements)
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“…In the present study, LGV2b (ST58) was isolated from three patients and ST108 from a third, demonstrating the global spread of these virulent strains. The ongoing epidemic of biovar L2b that was first identified in the Netherlands in 2003, mainly among HIV-positive MSM (Nieuwenhuis et al, 2004;Nieuwenhuis et al, 2003;Spaargaren et al, 2005), has spread globally to other industrialized countries (Martin-Iguacel et al, 2010;Kendall et al, 2014;Cabello Ubeda et al, 2016;Parra-Sanchez et al, 2016;Templeton et al, 2016;Isaksson et al, 2017;Latini et al, 2017). This is the first report of this biovar in Israel.…”
Section: Discussionmentioning
confidence: 89%
“…In the present study, LGV2b (ST58) was isolated from three patients and ST108 from a third, demonstrating the global spread of these virulent strains. The ongoing epidemic of biovar L2b that was first identified in the Netherlands in 2003, mainly among HIV-positive MSM (Nieuwenhuis et al, 2004;Nieuwenhuis et al, 2003;Spaargaren et al, 2005), has spread globally to other industrialized countries (Martin-Iguacel et al, 2010;Kendall et al, 2014;Cabello Ubeda et al, 2016;Parra-Sanchez et al, 2016;Templeton et al, 2016;Isaksson et al, 2017;Latini et al, 2017). This is the first report of this biovar in Israel.…”
Section: Discussionmentioning
confidence: 89%
“…A large percentage of men are HIV and/or hepatitis C positive and very few cases, if any, are detected in heterosexual men or women. Asymptomatic cases have been detected, but the vast majority of cases present with symptoms of rectal infection (14)(15)(16)(17)(18)(19).…”
Section: Discussionmentioning
confidence: 99%
“…LGV (99.8%) and non-LGV (95.1%) anorectal CT infections primarily affected men but some women with non-LGV anorectal CT infections were diagnosed (Table 1). Overall, men with LGV infections were older (median age [inter-quartile range (IQR)]¼ 41 [34-48])) than men with non-LGV (median age [IQR]¼32 [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41]) CT infections. MSM were predominant among cases of LGV and non-LGV anorectal CT infections, and comprised greater than 51 and 67% of the cases, respectively.…”
Section: Anorectal Lgv and Non-lgv Anorectal Ct Infectionsmentioning
confidence: 99%