Clinical Aspects and Side Effects of Therapy by Oral Administration of Retinoids in Various Skin Diseases

Konstantinović, S

doi:10.1007/978-3-642-68023-6_75

Cited by 2 publications

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“…The eczematous lesions im proved slightly, but were not completely curable. Since aromatic retinoid (Etretinate, Ro 10-9359, La Roche) has been shown to be effective for Darier's disease [6], On the other hand, we have studied the effect of top ical application with 0.1% aromatic retinoid ointment on guinea pig epidermis histolog ically, electron microscopically, and autoradiographically [7], Differentiation and pro liferation of the epidermis in guinea pigs af ter topical application of aromatic retinoid showed almost the same response in quanti ty as the epidermis after topical application of retinoic acid, while the epidermal alter ation was less than in the epidermis after topical application of retinoic acid. There fore, we used 0.1% aromatic retinoid oint ment in our patient and obtained favorable results without side effects.…”

Section: Discussionmentioning

confidence: 99%

A Case of Localized Darier’s Disease

Ueda¹,

Maruo²,

Matsubara³

et al. 1983

Dermatology

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A case of localized Darter’s disease was reported. The patient was a 36-year-old Japanese woman, and hyperkeratotic papules in zosteriforme arrangement were persistently noted on the left forehead since the age of 20 years. Histological appearance was same as in classical Darter’s disease. Skin atrophy due to long-term application of corticosteroid ointment was observed. Aromatic retinoid ointment was effective in the treatment of the lesions. The literature on localized Darter’s disease is reviewed.

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Section: Discussionmentioning

confidence: 99%

A Case of Localized Darier’s Disease

Ueda¹,

Maruo²,

Matsubara³

et al. 1983

Dermatology

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Vesiculobullous Hailey‐Hailey disease: Successful treatment with oral retinoids

Hunt

Salisbury

1996

Aust J Dermatology

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A 56-year-old male presented with a pruritic, generalized vesiculobullous eruption. His past history revealed classical symptoms of limited Hailey-Hailey disease for 34 years. Clinically, vesicles, bullae and occasional pustules were present and multiple biopsies confirmed this to be an unusual presentation of Hailey-Hailey disease. Various therapeutic modalities including topical and oral antibiotics, oral prednisone and dapsone failed to achieve sustained remission. Treatment with low-dose oral etretinate (25 mg daily) produced marked clinical improvement with complete suppression of new vesicle formation after 6 weeks.

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Clinical Aspects and Side Effects of Therapy by Oral Administration of Retinoids in Various Skin Diseases

Cited by 2 publications

References 0 publications

A Case of Localized Darier’s Disease

A Case of Localized Darier’s Disease

Vesiculobullous Hailey‐Hailey disease: Successful treatment with oral retinoids

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