Clinical Characteristics and Computed Tomography Findings in Arab Patients Diagnosed with Pulmonary Sarcoidosis

Alhamad, Esam H.; Alanezi, Mohammed O.; Idrees, Majdy; Chaudhry, Mohammad K.; Alshahrani, Ali; Isnani, Arthur; Shaikh, Shaffi

doi:10.5144/0256-4947.2009.454

Cited by 2 publications

(2 citation statements)

References 25 publications

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“…The prevalence of sarcoidosis in the Middle East is not known but it has been described in middle easterners, especially women 105 . Sarcoidosis can affect both upper respiratory airways 106 and/or lower respiratory tract causing lung functional impairment, 107 and can mimic chronic beryllium disease 108 . A retrospective study involving 104 Arabic patients revealed that 77% of newly diagnosed sarcoidosis patients were in their fifth decade or older at the time of presentation with a female : male ratio of 2:1 107 .…”

Section: Pulmonary Pathology In the Middle Eastmentioning

confidence: 99%

Respiratory disorders in the Middle East: A review

et al. 2011

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The spectrum of pulmonary pathology in the Middle East is as versatile as its civilizations and cultures. In this review, we outline the key challenges confronting pulmonologists in the Middle East. We shed light on the diverse conditions commonly encountered in the region, from the centuries-old illnesses of tuberculosis, to contemporary problems such as lung complications from chemical warfare. We specifically highlighted unique aspects related to respiratory illnesses in the Middle East, for example, climate factors in the desert region, cultural habits, for example, water-pipe smoking and disorders unique to the region, such as Behçet's disease. Pulmonologists are also faced with the consequences of modernization, including large immigrant population and associated social and health issues, rising incidence of obesity and sleep apnoea, and drug-resistant tuberculosis. Tackling these health issues will require an integrated approach involving public health, primary care as well as specialist pulmonology input, taking into consideration the unique cultural and environmental factors to ensure effective management and compliance to medical care.

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Section: Pulmonary Pathology In the Middle Eastmentioning

confidence: 99%

Respiratory disorders in the Middle East: A review

et al. 2011

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“…9 Sarcoidosis is diagnosed in patients across the globe with variable incidences, prevalence and courses of disease among different regions and ethnicities. 10 Sarcoidosis in the Middle East was previously addressed in some studies from Saudi Arabia, [11][12][13] Kuwait, 14 Oman, 15 Turkey, 6,16 Israel, 17,18 Iran 19,20 and Egypt. 21,22 In this study, we aimed to evaluate the clinical phenotypic features of sarcoidosis in a single-center academic hospital in Jordan.…”

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Sarcoidosis in Jordan: A Study of the Clinical Phenotype and Disease Outcome

et al. 2020

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Objectives: This study aims to evaluate the clinical phenotypic features of sarcoidosis in a single-center academic hospital in Jordan. Patients and methods: A retrospective file review was performed at an academic medical center in Jordan that included all patients diagnosed with sarcoidosis between January 2000 and December 2018. A total of 150 patients with sarcoidosis (38 males, 112 females; mean age 47.8±11.7 years; range, 17 to 79 years) were evaluated. Clinical data extracted from the files included the sex of the patient, the age at time of diagnosis, diagnosis date, the season during which the diagnosis was established, and smoking history. Biopsy histopathology, spirometry, nerve conduction, echocardiography, and imaging reports including plain radiographs, ultrasonographic, magnetic resonance and computed tomography reports were reviewed. Data including laboratory values, medication usage, clinical outcomes, and morbidity/mortality were collected. Pulmonary function tests including spirometry and lung volumes along with the diffusing capacity for carbon monoxide were reviewed for the presence of restriction, obstruction or reduction in the diffusion capacity of carbon monoxide. Identification of extra-thoracic organ involvement was determined in each patient in accordance with the criteria suggested by the updated World Association of Sarcoidosis and Other Granulomatous Disorders. Results: A total of 77.3% of the patients were diagnosed by biopsy. One case of Lofgren's syndrome was identified. Of the patients, 18.0% had isolated pulmonary sarcoidosis, 75.3% had pulmonary and extra-pulmonary sarcoidosis and 6.7% had isolated extra-pulmonary sarcoidosis while 81.3% had respiratory symptoms, mostly shortness of breath and cough. Extra-thoracic organ involvement mostly involved the musculoskeletal system (33%) followed by the skin (20%). Female patients had more extra-thoracic involvement but the sex difference was only statistically significant for cutaneous involvement. Of the patients, 84% received treatment while 20% had disease remission during the first two years after diagnosis and 70% required treatment beyond two years after diagnosis. Conclusion: Various sarcoidosis clinical phenotypes are seen among Jordanian patients. Jordanian females are more affected by the disease and have more extra-thoracic involvement compared to male patients. A large number of the study patients received treatment.

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Clinical Characteristics and Computed Tomography Findings in Arab Patients Diagnosed with Pulmonary Sarcoidosis

Cited by 2 publications

References 25 publications

Respiratory disorders in the Middle East: A review

Respiratory disorders in the Middle East: A review

Sarcoidosis in Jordan: A Study of the Clinical Phenotype and Disease Outcome

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