Clinical characteristics of adenovirus associated lower respiratory tract infection in children

Lu, Meiping; Ma, Liya; Zheng, Qi; Dong, Lili; Chen, Zhimin

doi:10.1007/s12519-013-0431-3

Cited by 44 publications

(65 citation statements)

References 15 publications

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“…In our study, 12.1% of the patients were found to be infected with viruses. A recent study showed that the positive detection rate of adenovirus by RT-PCR was 0.63% in children with pneumonia (24). Similarly, in our study, adenovirus was detected only in one patient in 2-11 months of age group.…”

Section: Discussionsupporting

confidence: 80%

Clinical characteristics and incidence of bacterial and viral pathogens in patients hospitalized with community acquired pneumonia in childhood in Konya between October 2008 and February 2010

Sert¹,

Emiroğlu²,

Arslan³

et al. 2016

Turk Hij Den Biyol Derg

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Section: Discussionsupporting

confidence: 80%

Clinical characteristics and incidence of bacterial and viral pathogens in patients hospitalized with community acquired pneumonia in childhood in Konya between October 2008 and February 2010

Sert¹,

Emiroğlu²,

Arslan³

et al. 2016

Turk Hij Den Biyol Derg

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“…In some studies, MP is considered as a cofactor in severe respiratory disease as it dampens the immune response and damages the epithelial cells (16).…”

Section: Discussionmentioning

confidence: 99%

“…HAdVs can cause a wide range of illnesses, from mild upper respiratory tract infections to serious diseases such as severe pneumonia (15). The detection rate of HAdV is 5% -7% in young children with respiratory illnesses (16). Unlike RSV, HMPV and influenza virus infections, HAdV infections have been reported mainly in children with viral co-infections (8).…”

Section: Introductionmentioning

confidence: 99%

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Detection of Respiratory Co-Infections in Children Less Than Five Years With Adenovirus Infection

Malekshahi

Shafiei-Jandaghi

Yavarian

et al. 2016

Arch Pediatr Infect Dis

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Background: Acute respiratory tract infection is associated with significant morbidity, mortality, and economic loss worldwide. Viral infections seem to be responsible for 80% of the cases. There are several reports on the influence of dual or multiple respiratory viral infections on the severity of disease in childhood. Objectives: A limited number of studies have been conducted on co-infection of Adenovirus (AdV) with coxsackievirus, human bocavirus (HBoV) and Mycoplasma pneumoniae (MP) in Iran. To address this, the present article focuses on both the etiology and epidemiology of multiple microbial respiratory infections (coxsackievirus, HBoV, MP and influenza virus) and their clinical significance in young Iranian children with confirmed AdV infection. Patients and Methods: Molecular detection of HBoV, coxsackievirus, MP and influenza virus was performed by conventional PCR in 71 respiratory adenovirus-positive samples obtained from children younger than 5 years of age. Results: Among the 71 adenovirus-positive samples, 6 (8.4%) were co-infected, three were co-infected with MP and three of which were co-infected with influenza A/H3N2. Of the six patients with co-infection, four were male and two were female; three patients were less than 1 year of age and the remaining were 2, 3 and 4 years of age. Moreover, there were two inpatients and four outpatients. Conclusions: Although several studies have investigated viral respiratory co-infection, no study has evaluated the rate of respiratory co-infections in adenovirus-positive samples from children younger than 5 years. However, this study has filled this gap, the the number of co-infections were too small to draw any definite conclusions. Therefore, large-scale studies using bigger samples are required to understand the clinical significance of polymicrobial acute respiratory infections.

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“…El género o el panel viral negativo no influyó en la edad promedio; sin embargo, la edad de presentación sí fue mayor cuando el panel viral fue positivo para otros virus diferentes al VSR o cuando se asociaron con él, especialmente en el sexo masculino (p=0,043), datos que coinciden con lo reportado por Sardón Prado y col, Gereige RS y cols y Mei-Ping Lu y col (14,15,16). En los pacientes que se hospitalizaron en más de una ocasión, pareciera que el hecho de presentar un primer episodio a edades más tempranas constituyera un factor de riesgo para su recurrencia.…”

Section: Discussionunclassified

Caracterización de la enfermedad respiratoria baja en pacientes menores de 5 años, hospitalizados en un centro de 3º nivel

P¹,

G²,

D³

et al. 2016

Rev. Med.

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Clinical characteristics of adenovirus associated lower respiratory tract infection in children

Cited by 44 publications

References 15 publications

Clinical characteristics and incidence of bacterial and viral pathogens in patients hospitalized with community acquired pneumonia in childhood in Konya between October 2008 and February 2010

Clinical characteristics and incidence of bacterial and viral pathogens in patients hospitalized with community acquired pneumonia in childhood in Konya between October 2008 and February 2010

Detection of Respiratory Co-Infections in Children Less Than Five Years With Adenovirus Infection

Caracterización de la enfermedad respiratoria baja en pacientes menores de 5 años, hospitalizados en un centro de 3º nivel

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