Clinical Course and Complications

Ultmann, John E.

doi:10.1001/archinte.1973.00320090022003

Cited by 41 publications

(2 citation statements)

References 248 publications

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“…'*4 Involvement by Hodgkin's disease is rare. 3 The largest reported series of this complication, indicates that breast carcinoma, lymphoma, and lung carcinoma, in order of decreasing frequency, are the most commonly associated neoplasms; only three were due to Hodgkin's d i~e a s e .~ Only sporadic documented reports of this complication are to be found in the litera-t~r e . ' *~-~ Because of the frequent difficulty in obtaining a cytologic diagn~sis,'.~ this problem may often be overlooked.…”

Section: Discussionmentioning

confidence: 99%

Hodgkin's disease with leptomeningeal involvement: Report of a case with long survival

Orlowski

Hansen

Anderson

et al. 1984

Cancer

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A 30‐year‐old white man with Stage IV B Hodgkin's disease, mixed cellularity type, developed leptomeningeal involvement shortly after relapsing on nitrogen mustard, Oncovin (vincristine), procarbazine, and prednisone (MOPP), and while receiving Adriamycin (doxorubicin), bleomycin, Velban (vinblastine), and dacarbazine (ABVD). Whole brain irradiation and intrathecal methotrexate were successfully incorporated into his treatment program. The patient has now been in complete remission for more than 40 months. A review of this rare complication of Hodgkin's disease is presented.

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Section: Discussionmentioning

confidence: 99%

Hodgkin's disease with leptomeningeal involvement: Report of a case with long survival

Orlowski

Hansen

Anderson

et al. 1984

Cancer

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“…The frequency of CNS involvement is 0.2%-0.5% in patients with advanced stage Hodgkin's lymphoma (HL) [2]. Leptomeningeal involvement in various malignancies is not common [3,4] and in Hodgkin's disease it is rare [5]. As such, herein we present an HL patient with involvement of the leptomeninges.…”

Section: ıNtroductionmentioning

confidence: 97%

Hodgkin's lymphoma with leptomeningeal involvement

Yildirim¹,

Gündoğdu²,

Erdem³

et al. 2011

Turk J Hematol

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A 31-year-old male patient with Hodgkin's lymphoma (Hl) and leptomeningeal involvement presented to at Hematology departments of Atatürk University . The patient developed dizziness, limb weakness, involuntary contractions of the hands and feet, incontinence, headache, fever, nausea, and vomiting following the first cycle of treatment with the ABVd protocol (adriamycin 25 mg m ⎯2, bleomycin 10 mg m ⎯2, vinblastin 6 mg m ⎯2 , and dacarbazine 375 mg m ⎯2 on d 1 and 15 of a 28-d cycle). magnetic resonance imaging (mRı) showed that there were regions with infiltration in particularly the thoracic vertebrae (T3, T4, T9, and T10-T12). ın the lumbar region leptomeningeal involvement beginning at the end of the medulla spinalis that gave rise to a separation of nerves in the cauda equine was observed. Contrast agent uptake was observed, especially at the dural sac, with edema in the nerve roots.Key Words: leptomeningeal involvement, Hodgkin's lymphoma Özet Otuz bir yaşında leptomeningeal tutulumu olan Hodgkin's lenfoma (Hl)'lı erkek hasta sunuldu. Hastada, ABVd (Adriamycin 25 mg/m2, bleomycin 10 mg/m2, vinblastine 6 mg/m2, dacarbazine 375 mg/m2 on days 1 and 15 of a 28-day cycle) tedavisinin ilk siklusundan sonra baş dönmesi, ekstremitelerde güçsüzlük, el ve ayaklarda istemsiz kasılma, inkontinans, baş ağrısı, ateş, bulantı ve kusma gelişti. magnetic resonance imaging (mRı)'da özellikle torakal vertebralarda (T3, T4, T9, T10-T12), infiltrasyon ile uyumlu alanlar görüldü. lomber bölgede medulla spinalisin son kısmından başlayan, kauda equinadaki sinirlerde ayrılmaya sebep olan leptomeningeal tutulum görüldü. Sinir köklerinde ödem ile birlikte özellikle dural kesede kontrast madde tutulumu görüldü.Anahtar Sözcükler: leptomeningeal tutulum, Hodgkin lenfoma

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Sputum Cytologic Diagnosis of Hodgkin's Disease Involving the Lung

Giangreco¹

1980

Arch Intern Med

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Clinical Course and Complications

Cited by 41 publications

References 248 publications

Hodgkin's disease with leptomeningeal involvement: Report of a case with long survival

Hodgkin's disease with leptomeningeal involvement: Report of a case with long survival

Hodgkin's lymphoma with leptomeningeal involvement

Sputum Cytologic Diagnosis of Hodgkin's Disease Involving the Lung

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