Clinical, dermoscopy and histological correlation study of melanotic pigmentations in excision scars of melanocytic tumours

Botella‐Estrada, Rafael; Nagore, Eduardo; Sopena, J.; Cremades, Antonio; Alfaro, Alberto; Sanmartín, O.; Requena, Celia; Serra‐Guillén, C.; Guillén, C.

doi:10.1111/j.1365-2133.2005.07105.x

Cited by 40 publications

(24 citation statements)

References 26 publications

(49 reference statements)

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“…Epidermolysis bullosa (EB) represents a heterogeneous group of mechano-bullous disorders genetically rooted in an intrinsic defect of the structural components of the basement membrane zone [1]. The development of lesions with atypical clinical features in patients with different forms of EB has occasionally been pointed out.…”

Section: Discussionmentioning

confidence: 99%

Epidermolysis Bullosa Nevi: Report of a Case and Review of the Literature

Fuscaldi¹,

Buçard²,

Alvarez³

et al. 2011

Case Rep Dermatol

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A 10-year-old female patient, being treated for dystrophic bullous epidermolysis in a Pediatric Hospital, was referred to our Dermoscopy Ambulatory because of a newly observed mole in the submandibular area. Clinically, the lesion presented as an irregular double-colored macule of about 2 cm in diameter, with irregular borders, suspicious of malignancy. Dermoscopy showed a multicomponent pattern, with multiple colors, ill-defined network, black blotches, streaks, multiple dots, a blue-whitish veil and granularity at the periphery. Although it had a clinical appearance of malignancy, dermoscopy every semester was proposed due to the revision of a recently described entity, named bullous epidermolysis nevi, that we made in these children. The fragile skin of this particular patient was also taken into account, and overtreatment was avoided. Bullous epidermolysis nevi is the term given to large, asymmetrical and often irregularly pigmented melanocytic nevi that occur in former areas of blistering in patients with the dystrophic forms of the disease. Despite its atypical clinical appearance, and sometimes also atypical dermoscopy, malignant transformation has not been reported yet. Similarly to recurrent nevi, where melanocytes proliferate in a previous area of trauma, clinical aspect, dermoscopy, and histopathology may tempt clinicians to diagnose benign moles as melanoma. Here we report one case of this entity, scarcely reported on in literature, and review clinical and dermatoscopical features of epidermolysis bullosa nevi confronting it with recurrent nevi. The usefulness of dermoscopy as a treatment strategy is stressed.

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Section: Discussionmentioning

confidence: 99%

Epidermolysis Bullosa Nevi: Report of a Case and Review of the Literature

Fuscaldi¹,

Buçard²,

Alvarez³

et al. 2011

Case Rep Dermatol

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“…According to the study by Botella-Estrada et al the presence of fine and homogeneous striae is associated with reactive pigmentation (p=0.026), and the spots with lesion recurrence (p <0.0001). 8 Applying the latter concept to the present case, the predominant structures are the striae and because it is not a case of melanocytic tumor excision scar we can not affirm that this is a reactive pigmentation or de novo melanocytic proliferation event, which justifies the regional biopsy. 9 …”

Section: Discussionmentioning

confidence: 57%

Case report: dermoscopic and histological aspects of skin graft and perigraft hyperpigmentation in acral location

Tuma

Yamada

Medeiros³

et al. 2014

An. Bras. Dermatol.

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Little is known about the use of dermoscopy in skin grafting. We describe the case of a patient with skin grafting and surrounding pigmentation on acral region. The dermoscopic findings were similar to those of benign acral lesions (lattice-like pattern) and reactive pigmentations (fine striae). Histopathology revealed pigment leakage and increased number of melanocytes. It is believed that this phenomenon occured as the result of an inflammatory stimulus.

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“…7 A study of the dermoscopic features of pigment recurrence in scars did not come across this phenomenon. 8 A recent study of the dermoscopic and confocal microscopic assessment of pigmentation associated with a scar from previous treatment showed extension of pigmentation beyond the scar in four cases that were melanomas. 6 Three cases that were recurrent naevi showed repigmentation within the scar.…”

Section: Discussionmentioning

confidence: 98%