Clinical experience in pemphigoid gestationis: Report of 10 cases

Castro, Luis Antônio Suíta de; Lundell, Ryan B.; Krause, Patricia K.; Gibson, Lawrence E.

doi:10.1016/j.jaad.2006.07.015

Cited by 71 publications

(51 citation statements)

References 31 publications

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“…Other histologic findings included dermal edema, mild perivascular inflammation with eosinophils, focal spongiosis, and epidermal ulceration. The histopathologic features of PG may vary greatly depending on the timing of the biopsy and the nature of the primary lesion [13][14][15]. Therefore, in many PG patients, nondiagnostic histologic findings are expected.…”

Section: Discussionmentioning

confidence: 99%

Pemphigoid gestationis: A Moroccan study

Chakiri¹,

Salim²,

Inani³

et al. 2017

Our Dermatol Online

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Section: Discussionmentioning

confidence: 99%

Pemphigoid gestationis: A Moroccan study

Chakiri¹,

Salim²,

Inani³

et al. 2017

Our Dermatol Online

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“…Clinical manifestations of pemphigoid gestationis include pruritus, urticarial and targetoid plaques, herpetiform vesicles, and tense bullae. 2,5 Lesions are most commonly located on the trunk (especially the periumbilical area) and the limbs but can involve the mucosa. The differential diagnosis of pemphigoid gestationis includes polymorphic eruption of pregnancy, linear IgA bullous dermatosis, bullous pemphigoid, dermatitis herpetiformis, erythema multiforme, Stevens-Johnson syndrome, and other drug eruptions.…”

Section: Discussionmentioning

confidence: 99%

“…3,6 Patient counseling is essential because pemphigoid gestationis usually recurs in subsequent pregnancies and may recur with the menstrual cycle and with oral contraceptive use. 1,5 Oral corticosteroids are the mainstay of treatment for pemphigoid gestationis. 3 In addition, breastfeeding has been reported to decrease disease duration.…”

Section: Discussionmentioning

confidence: 99%

Vesicles and Targetoid Lesions in a Postpartum Woman

Morganroth¹,

McHargue²

2014

JAMA Dermatol

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A woman in her 20s was seen with a widespread, intensely pruritic eruption that had started 4 days postpartum. The patient had had an uneventful pregnancy and did not have pruritus during her third trimester. Her child was born full-term, with no cutaneous lesions. Physical examination of the patient revealed an extensive cutaneous eruption involving all 4 extremities and most of her trunk, including the periumbilical area. There was no involvement of the ocular, oral, or external genital mucous membranes. Her skin lesions had multiple morphologies, including polycyclic vesicles overlying erythematous plaques on the lateral chest (Figure, A) and targetoid erythematous plaques with dusky centers on the abdomen (Figure, B). Punch biopsy specimens were obtained from a vesicle and perilesional skin and were submitted for histologic examination with routine hematoxylin-eosin staining (Figure, C) and direct immunofluorescence, respectively.

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“…It presents during pregnancy as periumbilical annular urticarial plaques which can spread to flexural areas and can vesiculate. 105 Affected women are usually in their second or third trimester, however it can present in the postpartum period as well. PG is unique in that it presents during pregnancy in clinically unaffected women and remits either immediately postpartum, or within weeks to months of delivery.…”

Section: What Is a Major Difference In Treating An Immunobullous Disementioning

confidence: 99%