Clinical Features of Multiple Glomus Tumors

Anakwenze, Okechukwu A.; Parker, Wendy L.; Schiefer, Terry K.; Inwards, Carrie Y.; Spinner, Robert J.; Amadio, Peter C.

doi:10.1111/j.1524-4725.2008.34173.x

Cited by 27 publications

(21 citation statements)

References 45 publications

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“…Glomangiomas can present in any location, such as the extremities, trachea, lungs, nasal cavity, stomach, kidneys, and others (Al-Ahmadie et al, 2007; Alempijevic et al, 2008; McKenna and Kerr, 2008; Miyamoto and Wada, 2009; Parker et al, 2010; Rao et al, 2010; Santambrogio et al, 2011). Though glomangiomas have the potential to present anywhere in the body, they most often present in the extremities (Anakwenze et al, 2008; Glazebrook et al, 2010). Because this condition is rare but often debilitating due to the pain of the tumors, surgical treatment is usually necessary for problematic lesions.…”

Section: Discussionmentioning

confidence: 99%

The use of stereotactic body radiation therapy for local control of glomangiomatosis: a case report

Horne¹,

Karam²,

Rashid³

et al. 2013

Front. Oncol.

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The vast majority of glomangiomas are small, benign neoplasms that can occur anywhere in the body but typically arise in the subcutaneous tissues of the extremities and are capable of causing extreme pain. Typically, these lesions are managed surgically with excellent rates of tumor control. On occasion, patients present with a variant of the glomangioma tumor consisting of numerous or recurrent nodules, a condition classified as glomangiomatosis. The authors present a case report of a young patient with multiply recurrent painful glomangiomas of the left foot, who was ultimately diagnosed with glomangiomatosis pedis. After multiple surgeries and surgical consultations, no surgery other than amputation was recommended. Therefore, the patient sought consultation with regard to stereotactic body radiation therapy (SBRT). In the absence of other options, and based on its effectiveness in treating glomus tumors of the head and neck which display similar natural history and histologic features, SBRT was offered. The patient underwent SBRT to the largest of his remaining tumors with excellent local control and significant reduction in pain at two and a half years follow-up.

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Section: Discussionmentioning

confidence: 99%

The use of stereotactic body radiation therapy for local control of glomangiomatosis: a case report

Horne¹,

Karam²,

Rashid³

et al. 2013

Front. Oncol.

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show abstract

“…A classic triad of pain, pinpoint tenderness with blunt palpation, and hypersensitivity to cold are noted. [4] Pain may be due to entrapment of myelinated nerve fibers by glomus cells. [5]…”

Section: Answersmentioning

confidence: 99%

“…It helps define the extent of the lesion and its relationship to other anatomic structures. [24] Plain radiography, angiography, thermography, ultrasound, and scintigraphy have all been used to diagnose glomus tumors with limited diagnostic success. [3]…”

Section: Answersmentioning

confidence: 99%

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An unusually painful nodule

et al. 2012

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“…Parsons et al 3 observed a positive family history in 60% of cases of multiple glomus tumors, transmitted by autosomal dominant inheritance with incomplete penetrance, with the responsible gene located on chromosome 1p21-22. 3,5,6 . Ectopic glomus tumors have been reported in the lungs, kidneys, bones, trachea and stomach.…”

Section: Case Reportmentioning

confidence: 99%