CLINICAL FEATURES, TOTAL AND SPECIFIC IgE SERUM CONCENTRATIONS OF PATIENTS WITH ATOPIC DERMATITIS AT CAN THO HOSPITAL OF DERMATO-VENEREOLOGY

Abstract

Background: Atopic dermatitis is a common skin disease in children as well as in adults, with the important feature of being recurrent. Immune disorders (the role of Specific IgE serum) have a relation to the severity of the disease and the risk of allergy in patients. Objectives: 1). To describe the clinical features of patients with atopic dermatitis at Can Tho Hospital of DermatoVenereology in 2021; 2). To determine the total and specific IgE serum concentration in patients with atopic dermatitis at Can Tho Hospital of Dermato-Venereology in 2021. Materials and methods: A cross-sectional descriptive study was carried out on 50 patients with atopic dermatitis hospitalized at Can Tho Hospital of Dermato-Venereology. Results: The rate of itching and types of eczematous lesions accounted for 100%, skin lesions with typical morphology and age-specific patterns were approximately 92%, chronic or relapsing history held 80%, xerosis rate was up to 82%, early age of onset made up 18%, the rate of increase in total and specific IgE serum level in patients with atopic dermatitis was 54% and 84%, respectively, the mean total IgE serum concentration was 210.01 ± 157.88 IU/mL, the lowest was 6.54 IU/mL and the highest was 741.23 IU/mL. D. pteronyssinus and D. farina accounted for the highest proportion of respiratory allergens (46%), cocoa beans accounted for the highest proportion of food allergens (28%). Conclusions: Atopic dermatitis in adult patients associated with pruritus, D. pteronyssinus and D. farina in respiratory allergens and cocoa beans in food allergens was the most common. Total and specific serum IgE concentrations are often elevated in patients with atopic dermatitis.