Clinical, histopathological and immunohistological study of lymphoid disorders in the parotid gland of patients with Sjögren's syndrome

Mt, Bozinović; Katić,; Krasić, Dragan; Veselinović, Dragan; Jovanovič, Petra; Krstić, Miljan

doi:10.2298/vsp0912955t

Cited by 4 publications

(1 citation statement)

References 16 publications

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“…This is of paramount importance in smaller medical centers where pathologists are not capable to analyze specimens immediately. In addition, the CNB preserves the histological architecture increasing the preciseness of the diagnosis and enabling the additional diagnostic procedures such as an immunohistochemically analysis 22 . The advantages of CNB are documented especially in cytological diagnosis of pleomorphic adenoma, Wartin's tumor and lymphoma that are traditionally hard to diagnose using only FNAC 23,24 .…”

Section: Fig 2 -Histology Of Tumors In the Parotid Salivary Gland: Amentioning

confidence: 99%

The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors

et al. 2019

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Background/Aim. The diagnosis of tumors of salivary glands relies heavily on radiological examination and biopsy of pathological tissue. The aim of this study was to investigate the sensitivity, specificity and accuracy of core needle biopsy in diagnosis of tumors of parotid and submandibular glands. Methods. This study was designed as a crosssectional clinical trial performed between May 2008 and Мay 2015 at the Department of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center Zemun, Belgrade, Serbia. The examinations included 200 patients among which 100 were diagnosed with tumors of parotid salivary glands and 100 with tumors of submandibular salivary glands. The core needle biopsy was undertaken in all cases where tumor was smaller than 2 cm, far from blood vessels and far from the deep layer of parotid gland. The histopathological analysis was performed to identify histological type of the lesion. Upon performing the surgical procedure and consequently the tumor tissue extirpation, tissue samples obtained were investigated for the definitive diagnosis. Results. The sensitivity of the procedure was 90.9% for parotid salivary gland and 74% for submandibular salivary gland, the specificity was 95.9% for parotid salivary gland and 93% for submandibular salivary gland and the accuracy was 94.7% for parotid salivary gland and 87% for submandibular salivary gland. Based on the histopathological findings of the salivary glands obtained using core needle biopsy of the tumor tissue, it was possible to differentiate between malignant and benign lesions. Conclusion. Current investigation points to the advantages and efficiency of core needle biopsy in diagnosis of tumors of parotid and submandibular salivary glands. Oroz A, et al. Vojnosanit Pregl 2019; 76(9): 921-928. nalaza biopsije šupljom iglom bilo je moguće diferencirati maligne od benignih lezija. Zaključak. Sprovedeno istraživanje ukazuje na prednost i efikasnost biopsije šupljom iglom u dijagnozi tumefakata doušne i podvilične pljuvačne žlezde.Ključne reči: biopsija tankom iglom; biopsija iglom; dijagnoza; histološke tehnike; parotidne žlezde, neoplazme; senzitivnost i specifičnost; submandibularne žlezde, neoplazme.

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Section: Fig 2 -Histology Of Tumors In the Parotid Salivary Gland: Amentioning

confidence: 99%

The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors

et al. 2019

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Indicators for Malignant Transformation in Patients With Lymphoepithelial Lesion

Zhang

Xia

et al. 2021

Journal of Oral and Maxillofacial Surgery

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Cytohistologic Features of Salivary Gland Lymphomas

Lubin

Lin

2020

AJSP: Reviews and Reports

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Clinical, histopathological and immunohistological study of lymphoid disorders in the parotid gland of patients with Sjögren's syndrome

Abstract: The optimal diagnosis of salivary gland MALT lymphoma requires careful integration of clinical, morphological and immunohistochemical results.

Cited by 4 publications

References 16 publications

The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors

The determination of specificity, sensitivity and accuracy of core needle biopsy in the diagnosis of parotid and submandibular salivary glands tumors

Indicators for Malignant Transformation in Patients With Lymphoepithelial Lesion

Cytohistologic Features of Salivary Gland Lymphomas

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