Clinical Impact of Comprehensive Molecular Profiling in Adolescents and Young Adults with Sarcoma
Eden C. Andrew,
Jeremy Lewin,
Jayesh Desai
et al.
Abstract:Sarcomas are a heterogenous group of tumours that commonly carry poor prognosis with limited therapeutic options. Adolescents and young adults (AYAs) with sarcoma are a unique and understudied patient population that have only achieved modest survival gains compared to other groups. We present our institutional experience of AYAs with sarcoma who underwent comprehensive molecular profiling (CMP) via either large-panel targeted DNA sequencing or whole genome and transcriptome sequencing and evaluated the feasib… Show more
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