2023
DOI: 10.1055/s-0043-1772684
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Clinical implication of changes in serum cations and anions on clinical severity in sickle cell disease: A case–control study in a tertiary center

Suprava Patel,
Diksha Chandrakar,
Preetam Narayan Wasnik
et al.

Abstract: Introduction Vaso-occlusive crisis in sickle cell disease (SCD) is related to disproportionate serum ions distribution. The objective was to evaluate the influence of changes in serum cations and anions on clinical severity in SCD patients. Materials and Methods The case–control study included 26 SCD cases and 27 apparently healthy control individuals. The cases were further grouped as crisis state and steady state cases. Each participant was assigned a disease severity score. All study participants … Show more

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