2020
DOI: 10.21203/rs.3.rs-131551/v1
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Clinical Performance of the ExoDx (EPI) Prostate Intelliscore Test to Predict High-grade Prostate Cancer at Initial Biopsy: A Pooled Analysis of Three Independent Prospective Studies.

Abstract: BACKGROUND The ability to discriminate indolent from clinically significant prostate cancer (PC) in the initial biopsy setting remains an important health issue. ExoDx Prostate(IntelliScore) (EPI), is a non-invasive exosome based liquid biopsy test that quantifies three RNA targets in exosomes from urine. The EPI test is used to help stratify patients for risk of high grade prostate cancer, HGPC (≥ GG2 PC) in men 50 years or older with PSA in the gray zone (2–10 ng/mL). The EPI test has been extensively valida… Show more

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“…Organ-wise, prostates in men are situated close to the bladder. Therefore, some of the works focused on prostate cancer at initial biopsy have been presented by Margolis in [21,22] to show the clinical performance of ExoDX (EPI) Prostate Intelliscore test. Moreover, the existing research shows the essentiality of research to find out the most impacting biomarkers in bladder cancer as well.…”
Section: Related Workmentioning
confidence: 99%
“…Organ-wise, prostates in men are situated close to the bladder. Therefore, some of the works focused on prostate cancer at initial biopsy have been presented by Margolis in [21,22] to show the clinical performance of ExoDX (EPI) Prostate Intelliscore test. Moreover, the existing research shows the essentiality of research to find out the most impacting biomarkers in bladder cancer as well.…”
Section: Related Workmentioning
confidence: 99%