Clinical predictive criteria associated with live birth following elective single embryo transfer

The influence of body mass index on pregnancy outcome following single-embryo transfer

“…Cases included in those reviews had considerable clinical and methodological heterogeneity in the transfer of multiple embryos and transfer of fresh or frozen embryos, with an inconsistent adjustment for risk factors. Studies on single-embryo transfers showed that obesity was negatively associated with the occurrence of live birth [24]. A retrospective study found that morbid obesity significantly increased miscarriage rates and reduced live birth rates [25].…”

Morbid obesity and pregnancy outcomes after single blastocyst transfer: a retrospective, North American study

“…Several studies have been published examining the effects of maternal BMI on IVF outcomes in patients specifically undergoing SBT [8,14,15]. All studies were based out of countries in Europe including the United Kingdom [8] and France [14,15]. As previously noted, the majority of patients within these studies fell under a BMI of 30 kg/m 2 .…”

“…Lastly, maternal BMI appears to affect pregnancy outcomes following SET even at the cleavage stage. Sifer et al [15] retrospectively examined 409 eSET on day 2/3 and found BMI to be the only clinical criteria statistically associated with LBR.…”

“…Therefore, it is important to identify patient factors that may compromise pregnancy outcomes after SBT. Recent observational studies examining clinical factors that predict IVF outcomes following SBT have all identified BMI as an independent predictor of LBR and miscarriage rate (MR) [13][14][15]. It is important to note, however, that these studies examined European populations with a BMI ranging between 18.6 and 34.9, with a large proportion of patients under a BMI of 30 kg/m 2 .…”

Association between maternal prepregnancy body mass index and pregnancy outcomes following assisted reproductive technology: A systematic review and dose–response meta‐analysis

“…In the final analysis, 105 eligible studies (19 prospective and 86 retrospective cohort studies) were included, involving more than 271,632 pregnant women (Figure 1). 14,15,28–130 The main characteristics of included studies were summarized in Table S1. In total, 100 studies reported the association between maternal BMI and CPR among pregnant women undergoing ART, among which 53 reported MR and 51 reported LBR (Table S1).…”