Clinical problems in patient with Ehlers-Danlos syndrome and Multiple Chemical Sensitivity undergoing total thyroidectomy

Treating pain in patients with Ehlers–Danlos syndrome

“…On the other hand, an impaired absorption capacity of the gastrointestinal tract due to compromised peristalsis reduces the oral bioavailability of drugs [40]. Lastly, the possibility of a pharmacogenetically determined, altered metabolism of analgesics should also be considered in EDS [41,42]. In practice, it has proven useful to start with low doses and, if possible, to initially avoid combining several substances in order to be able to directly assign unexpected reactions to a specific preparation.…”