Clinical studies on the effect of Neem (Azadirachta indica) bark extract on gastric secretion and gastroduodenal ulcer

Novel Anti-inflammatory Activity of Epoxyazadiradione against Macrophage Migration Inhibitory Factor

“…Neem (Azadirachta indica A. Juss) is a well known versatile medicinal plant that has a wide spectrum of biological activities including anti-inflammatory activity (33)(34)(35)(36)(37). The ethnopharmacological exploration and bioactivity testing of various neem compounds and extracts revealed its efficacy to prevent a wide variety of inflammatory disorders in infectious and non-infectious diseases (34, [37][38][39][40][41][42][43][44][45]. It is interesting to note that neem compounds show a beneficial effect in pathological conditions in which MIF-mediated pathologies are prevalent (6,10,11,14,16,17,21).…”

Gastroprotective effect of Desmodium gangeticum roots on gastric ulcer mouse models

“…In recent years, many countries with important biodiversity resources are developing and using nontoxic preparations from medicinal plants for controlling various diseases, providing relief of symptoms comparable to that obtained from allopathic medicine (Bandyopadhyay et al, 2004). Among the conditions that can possibly profit from traditional medicine are gastrointestinal diseases, particularly gastric and duodenal ulcers.…”

Pharmacology of Traditional Herbal Medicines and Their Active Principles Used in the Treatment of Peptic Ulcer, Diarrhoea and Inflammatory Bowel Disease

“…The bark extract completely healed the duodenal ulcers at the dose of 30-60 mg twice daily for 10 weeks (Bandyopadhyay et al, 2004). Some important blood parameters for organ toxicity such as sugar, urea, creatinine, serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, albumin, globulin, hemoglobin levels and erythrocyte sedimentation rate remained unaffected upon Neem exposure.…”