2019
DOI: 10.31234/osf.io/vks3u
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Clinically-Feasible Brain Morphometric Similarity Network Construction Approaches with Restricted Magnetic Resonance Imaging Acquisitions and their Relationship with Cognition

Abstract: Morphometric Similarity Networks (MSNs) estimate structural 'connectivity' as a biologically meaningful set of statistical similarities between cyto-architectural features derived in-vivo from multiple MRI sequences. These networks have shown to be clinically relevant, predicting 40% variance in IQ. However, the sequences required (T1w and T2w 3D anatomical, DWI) to produce these networks typically have long acquisition times, which are less feasible in some populations. Thus, estimating MSNs using features fr… Show more

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